7. Heart Failure/Cardiomyopathy Flashcards
contributing factors of SV
- preload
- afterload
- contractility
contractility is independent of
preload and afterload
estimate afterload
MAP
SBP
afterload impact on CO
inversely related
preload estimateion
LVEDP estimated by PAWP
all forms of heart disease have
high ventricular end diastolic pressure
does LVEDV increase with LVEDP
not necessarily
estimate for LVEDP
PAWP
estimate LVEDV
LVEDV ~ CO = HR*SV
Cardiac index
CI= CO/BSA
normal CI
2.5-4.2L/min/m2
Systolic heart failure
decr EF
chronic LV systolic dysfunction
systolic HF compensatory mechanism
tachycardia to incr CO
diastolic HF
inadequate relaxation of heart
improper filling
diastolic HF compensatory mechanism
tachycardia will decr CO
- better to be bradycardic to allow for adequate filling
general HF compensatory mechs
decr Vmax
incr afterload
incr sympathetics
incr vascular tone
frank starling HF compensation
fluid retention/resuscitation
higher filling pressures needed to achieve similar SV/CO
incr afterload causes
heart needs to work harder
myocardial remodeling processing
hypertrophy
dilation
wall thining
incr collagen
myocardial fibrosis
scar formation
myocyte death
compensatory mechanism for pressure overlad
myocardial hypertrophy
myocardial hypertrophy is a _____ state
lower inotropic state
compensatory mechanism for fluid overload
dilation
most common cause of myocardial remodeling
ischemic injury