7. Heart Failure/Cardiomyopathy Flashcards
contributing factors of SV
- preload
- afterload
- contractility
contractility is independent of
preload and afterload
estimate afterload
MAP
SBP
afterload impact on CO
inversely related
preload estimateion
LVEDP estimated by PAWP
all forms of heart disease have
high ventricular end diastolic pressure
does LVEDV increase with LVEDP
not necessarily
estimate for LVEDP
PAWP
estimate LVEDV
LVEDV ~ CO = HR*SV
Cardiac index
CI= CO/BSA
normal CI
2.5-4.2L/min/m2
Systolic heart failure
decr EF
chronic LV systolic dysfunction
systolic HF compensatory mechanism
tachycardia to incr CO
diastolic HF
inadequate relaxation of heart
improper filling
diastolic HF compensatory mechanism
tachycardia will decr CO
- better to be bradycardic to allow for adequate filling
general HF compensatory mechs
decr Vmax
incr afterload
incr sympathetics
incr vascular tone
frank starling HF compensation
fluid retention/resuscitation
higher filling pressures needed to achieve similar SV/CO
incr afterload causes
heart needs to work harder
myocardial remodeling processing
hypertrophy
dilation
wall thining
incr collagen
myocardial fibrosis
scar formation
myocyte death
compensatory mechanism for pressure overlad
myocardial hypertrophy
myocardial hypertrophy is a _____ state
lower inotropic state
compensatory mechanism for fluid overload
dilation
most common cause of myocardial remodeling
ischemic injury
treatment for myocardial remodeling
ACE inhibitors
aldosterone inhibitors
cardiomegaly
alveolar edema
(pulm venous congestion severity level 3)
pulmonary edema
pleural effusion
pericardial effusion
acute HF management
loop diuretics
vasodilators
- NTG
- nipride
inotropes
- epi/Ne
- dobutamine
- milrinone
BNP
balloon pump
PVAD
balloon pump: systole
deflates
suction incr EF
balloon pump: diastole
inflates
incr CPP
causes of RHF
Left ventricular failure
pulmonary HTN
right heart MI
most common cause of RHF
left ventricular failure
causes of LHF
left heart MI (LAD)
chronic HTN
acute HTN crisis
aortic/mitral valve disease
high output HF
normal cardiac function
unable to provide adequate perfusion
high output HF diagnostic values
CO > 8L/min
CI > 4L/min2
causes of high output HF
hyperthyroid
sepsis
beriberi
lung disease
arteriole/capillary bypass
severe anemia
pregnancy
HR: 65
BP: 80/45
SVR: 1400
CI: 1.5
PA: 40/20
Treatment?
milrinone
- incr inotropy
- decr PAP
HR: 65
BP: 80/45
SVR: 650
CI: 3.0
PA: 20/10
Treatment?
NE
- incr SVR
HRL 50
BP: 80/45
SVR: 650
CI: 1.0
PA: 20/10
Treatment?
Epi
- incr HR
- incr inotropy
- incr SVR
post heart transplant
immunocompromised
need direct acting beta agonists (Phenylephrine)
pre-load dependent
avoid fluid overload
HR: 60
BP: 80/45
SVR: 1200
CR: 1.0
PA: 20/10
Treatment?
dobutamine
- incr inotropy
hypertrophic cardiomyopathy anatomic changes
septum hypertrophy
absence of cardiac disease
LVOT
factors that worsen LVOT
incr contractility
- beta stimulation
decr preload
- hypovolemia
- vasodilators
- tachycardia
- PPV
decr afterload
- hypotension
- vasodilators
PPV
factors that improve LVOT
decr contractility
- beta blockers
- VA
- CCB
incr preload
- hypervolemia
- bradycardia
incr afterload
- HTN
- alpha adrenergics
goals for HCM
decr LVOT
minimize ischemia
avoid arrythmias
anesthetic managment for HCM
beta blockers
CCB
euvolemia
mx SVR
mx sinus
avoid contractilioty changes
what drugs worsen LVOT
ephedrine
dobutamine
epi
HCM pregnancy management
epidurals
hypotension: fluid+phenylephrine
labor worsens LVOT
dilated cardiomyopathy anatomic changes
LV dilation
regional wall abnormalities
valvular abnormalities
DCM anesthetic management
treat like HF
give anticoag
regional if not on anticoag
peripartum cardiomyopathy treatment
diuretics
vasodilators
peripartum cardiomyopathy is ______
dilated cardiomyopathy
restrictive cardiomyopathy characteristic
severe diastolic dysfunction
incr stiffness of myocardium
restrictic cardiomyopathy management
sinus
avoid bradycardia
mx venous return
euvolemia
ketamine induction
avoid PPV
cor pulmonale
right ventricular enlargement (hypertrophy and/or dilation)
may progress to RHF
causes of Cor pulomonale
COPD
restrictive lung disease
pulm artery HTN
cor pulmonale management
euvolemia
ABG
avoid hypoxia
avoid hypercarbia
avoid overnarcs