6.3 Meiosis Flashcards
Reduction division
Gametes formed via meiosis form 4 daughter cells due to the nucleus dividing twice
–> each gamete contains half of the chromosome number (haploid)
Homologous chromosomes
each nucleus of organism’s cells contain two full sets of genes, a pair of genes for each characteristic. Therefore, each nucleus contains matching sets of chromosomes (homologous chromosomes)
Alleles
different versions of the same gene that code for a specific characteristic
–> found in the same locus
–> homologous chromosomes have same genes in same positions= same length and size, centromeres in same position
Meiosis I
first division (reduction division ) when pair of homologous chromosomes are separated into two cells
–> each intermediate cell will only contain one full set of genes (haploid)
Meiosis II
second division is similar to mitosis & pairs of chromatids present in each daughter cell are separated, forming two more cells
–> 4 haploid cells in total
Prophase I (Meiosis I)
Chromosomes condense; nuclear envelope disintegrates; nucleolus disappears and spindle formation begins, as in prophase of mitosis
Difference: homologous chromosomes line up to form bivalents
–> Chromosomes are large molecules of DNA & moving them through cytoplasm to bring them together results in entanglement: crossing over)
Bivalent
homologous chromosomes that are in a synapse during meiosis
–> 2 chromosomes and 4 arms/ chromatids (Known as a tetrad)
Metaphase 1 (Meiosis I)
same as metaphase except PAIR of chromosomes assemble along metaphase plate (not individual chromosomes)
–> ORIENTATION of each pair is random and independent to any other pair.
–> Individual assortment: Maternal or paternal chromosomes can end up facing either pole (allows many different combinations and results in genetic variation)
Anaphase 1 (Meiosis I)
DIFFERENT TO MITOSIS: homologous chromosomes are pulled to opposite poles and chromatids stay joined to each other
–> Sections of entangled DNA on chromatids now break off and rejoin together (sometimes causes an exchange of DNA: Chiasmata)
Chiasmata
points at which the chromatids break and rejoin
How does genetic variation arise at the anaphase 1 of meiosis I
when exchange occurs, recombinant chromatics are formed with genes being exchanged between chromatids
–> genes being exchanged may be different alleles of the same gene, resulting in combinant of alleles on recombinant chromatids will be different from allele combination on either original chromatic
–> genetic variation arises from this new combination of alleles (sister chromatids are no longer identical)
Telophase 1 (Meiosis I) & cytokinesis 1
SAME AS MITOSIS: chromosomes assemble at each pole & nuclear membrane reforms as chromosomes uncoil
Cell undergoes cytokinesis and divides into two (reduction of chromosome number from diploid to haploid is complete
Prophase 2 (Meiosis II)
Chromosomes (still consists of 2 chromatids) condense & become visible again
–> nuclear envelope breaks down and spindle formation begins
Metaphase 2 (Meiosis II)
DIFFERENT from metaphase 1: individual chromosomes line up on metaphase plate
–> due to crossing over, chromatids are no longer identical (some longer than others)
–> independent assortment occurs again and more genetic variation is produced
Anaphase 2 (Meiosis II)
Anaphase 2 results in chromatids of individual chromosomes being pulled to opposite poles after division of centromeres (same as mitosis anaphase)