6.1 Subcutaneous Flashcards

1
Q

Majority of the causative agents of mycoses are

a. Endosaprophyts
b. Exosaprophytes

A

b

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2
Q

Most common site for chromoblastomycosis?

a. Lower limb
b. Upper limb
c. Any area

A

a

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3
Q

In Chromoblastomycosis, secondary infection is common

T or F

A

T

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4
Q

Also called as copper pennies, this indicates chromoblastomycosis without indicating which fungus is the etiologic agent of the infection

a. Sclerotic bodies
b. Puffer bodies
c. Chromo bodies
d. None of the above

A

a

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5
Q

This caracterized as Verruoid crusted lesions and is not treated it resembles cauliflower

a. Chromoblastomyces
b. Mycetoma
c. Sporotrichosis
d. Phaeohyphomycosis

A

a. Chromoblastomyces

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6
Q

Phialophora verrucosa

a. Chromoblastomyces
b. Mycetoma
c. Sporotrichosis
d. Phaeohyphomycosis

A

a

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7
Q

Fonsecaea pedrosi and compacta

a. Chromoblastomyces
b. Mycetoma
c. Sporotrichosis
d. Phaeohyphomycosis

A

a

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8
Q

Cladophialophora carrionii

a. Chromoblastomyces
b. Mycetoma
c. Sporotrichosis
d. Phaeohyphomycosis

A

a

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9
Q

Most commonly observed in humid climates

a. F. pedrosoi
b. C. carrionii
c. F. monophora

A

a

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10
Q

Infection is normally found in dry areas
a. F. pedrosi
b. C. carrionii
c. F. monophora

A

b

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11
Q

Most common occupation in patients with chromobalstomycosis

a. farmers
b. Medtech
c. Factory workers
d. Fisherman

A

a

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12
Q

The predominant etiologic agent of chromoblastomycosis in southern China

a. F. pedrosoi
b. C. carrionii
c. F. monophora

A

c

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13
Q

Both Cladosporium carrionii and Fonsecaea pedrosoi causes dark olive-green/gray-green to grayish lavender with jet black reverse

T or F

A

T

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14
Q

Specimen for Chromoblastomycosis are skin scapins and aspirates

T or F

A

T

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15
Q

Stains used for Chromoblastomycosis are H&E, PAS digest, GMS

T or F

A

T

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16
Q

Primary isolation media in Chromoblastmycosis

a. SDA
b. BAP
c. PTA

A

a

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17
Q

Swollen tumor-like areas with sunuses that dran through multiple sinus tracts

a. Chromoblastomyces
b. Mycetoma
c. Sporotrichosis
d. Phaeohyphomycosis

A

b

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18
Q

Chronic granulomatous infection
a. Chromoblastomyces
b. Mycetoma
c. Sporotrichosis
d. Phaeohyphomycosis

A

b

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19
Q

Most common site for mycetoma?
a. Lower limb
b. Upper limb
c. Any area

A

a

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20
Q

Watering can foot / Madura foot

a. Chromoblastomyces
b. Mycetoma
c. Sporotrichosis
d. Phaeohyphomycosis

A

b

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21
Q

White to yellow grains are indicative of Pseudallescheria boydii

T or F

A

T

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22
Q

Secondary bacterial infection is common in mycetoma

T or F

A

t

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23
Q

Only surgical removal is successful
a. Chromoblastomyces
b. Mycetoma
c. Sporotrichosis
d. Phaeohyphomycosis

A

b

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24
Q

Yields the best result for the treatment of mycetomas

a. Itraconazole
b. Ketoconazole

A

a

b is alternative

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25
Q

Telemorph: Same as the name
Reservoir: Temperate and subtropical zones
2 asexual forms
- Scedosporium aspiospermum
- Graphium species

a. Exophiala jeanselmei
b. Pseudallescheria boydii

A

b

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26
Q

Cycloheximide is used in culture for Pseudallescheria boydii

T or F

A

F

Does not use it, other agents are

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27
Q

Oatmeal agar causes cleistothecia in pseudollascheria boydii (Mycetoma)

T or F

A

T

28
Q

Lollipop appearance in sexual state is observe in microscope

a. Exophiala jeanselmei
b. Pseudallescheria boydii

A

b

29
Q

Teleomorph: None
Reservoirs: Soil, on trees, rotting wood, decaying vegetation

Direct examination: Granules resemble flecks of black pepper

a. Exophiala jeanselmei
b. Pseudallescheria boydii

A

a

30
Q

Sporothrix schenckii
a. Chromoblastomyces
b. Mycetoma
c. Sporotrichosis
d. Phaeohyphomycosis

A

c

31
Q

Chronic infection characterized by nodular lesions of cutaneous or subcutaneous tissues of adjacent that suppurate , ulcerate and drain

a. Chromoblastomyces
b. Mycetoma
c. Sporotrichosis
d. Phaeohyphomycosis

A

c

32
Q

Most common site for Sporotrichosis
a. Upper Limbs
b. lower limbs
c. Any area

A

a, b

33
Q

Primary lesions develop at the site of implantation:
- feet / legs
- Hands / Arms

Localized w/o fever or malaise

Pathognomonic

a. Lymphocutaneous sporotrichosis
b. Fixed cutaneous sporotrichosis
c. Pulmonary sporotrichosis

A

a

34
Q

Primary lesions develop at the site of implantation:
- Limbs, Hands, Fingers
- Remains localized at entry point

a. Lymphocutaneous sporotrichosis
b. Fixed cutaneous sporotrichosis
c. Pulmonary sporotrichosis

A

b

35
Q

Inhalation of onidia
Haematogenous dissemination

Lung lesion: Gradual progression to death

a. Lymphocutaneous sporotrichosis
b. Fixed cutaneous sporotrichosis
c. Pulmonary sporotrichosis

A

c

36
Q

No telemorph
“Rose gardener’s disease

a. Exophiala jeanselmei
b. Pseudallescheria boydii
c. Sporothrix schenckii

A

c

37
Q

Clinical material for sporotrichosis

a. Sputum
b. Tissue biopsy
c. Broncho aspirate
d. Saliva

A

b

38
Q

Asteroid bodies can only be seen in sporotrichosis

T or F

A

T

39
Q

Primary isolation media used in sporotrichosis is:

a. SDA
b. BHIA with 5% sheep blood agar
c. All of the above

A

c

40
Q

Thermal dimophism is characteristical feature for sporothrix

T or F

A

T

41
Q

At 25-30 Leathery black or mottled black
At 35-37 Cream to tan yeastlike colony

T or F

A

T

42
Q

Serology used in sporotrix is indirect fluorescent antibody

T or F

A

F

Direct

43
Q

Infections tend to be chronic and localized in hosts and spread rapidly in immunocompromised patients.

The initial lesion is cystic (forms sac filled with
fluid) followed by necrosis.

Disease expands via satellite colonies

a. Chromoblastomyces
b. Mycetoma
c. Sporotrichosis
d. Phaeohyphomycosis

A

d

44
Q

Exophiala jeanselmei and Wangiella dermatitidis is common in

a. subcutaneous Phaeohyphomycosis
b. Paranasal Sinus Phaeohyphomycosis
d. Cerebral Phaeohyphomycosis

A

a

45
Q

Allergic rhinitis (Sinusitis) + Immunesuppression

a. subcutaneous Phaeohyphomycosis
b. Paranasal Sinus Phaeohyphomycosis
d. Cerebral Phaeohyphomycosi

A

b

46
Q

Rare infection
Immunosuppressed
Fungus is neutropic

a. subcutaneous Phaeohyphomycosis
b. Paranasal Sinus Phaeohyphomycosis
c. Cerebral Phaeohyphomycosi

A

c

47
Q

Clinical material for Phaeohyphomycosis are:
Skin biopsy
Sputum
CSF
Indwelling catheter tips

T or F

A

T

48
Q

Primary isolation for Phaeohyphomycosis is SDA

T or F

A

T

49
Q

Serology used in Phaeohyphomycosis is ELISA

T or F

A

F

No serology

50
Q

May also cause
chromoblastomycosis
Young black yeast colonies

Dark olive-green to black
colonies w/ black reverse

Slow growth (2-3 weeks)

Flask-shaped/cylindrical/vaseshaped phialides

Pigmented brown-green hyphae
& sclerotic bodies in specimens

a. Phialophora Verrucosa
b. Wangiella dermititidis

A

a

51
Q

Young black yeast colonies
(young cultures contain yeast
cells that technically belong to
the genus Phaecoccomyces, its
anamorph)

Mature olive-gray to black mould
colonies w/ black reverse

10-25 days

Pigmented hyphae &
phialoconidia, w/ pale brown
phialides

Pigmented brown hyphal
fragments- w/o granules or
sclerotic bodies in specimens

a. Phialophora Verrucosa
b. Wangiella dermititidis

A

b

52
Q

These are primitive, fast growing, terrestrial, largely, saprophytic fungi

a. Zygomycosis
b. Lobomycosis

A

a

53
Q

The most acute and fulminae fungal infection known

Typically involves rhino-facial-cranial area

a. Zygomycosis
b. Lobomycosis

A

a

54
Q

It is often associated with acidotic diabetes, starvation, severe burns, intravenous drug abuse, and other diseases such as leukemia and lymphoma, immunosuppressive therapy, or the use of cytotoxins and corticosteroids, therapy with desferrioxamine

Iron related problems

a. Zygomycosis
b. Lobomycosis

A

a

55
Q

Mucorale - Causing subcutaneous and systemic zygomycosis

Rhizopus

T or F

A

T

56
Q

is a slowly progressing tropical
infection of the subcutaneous tissue or paranasal sinuses caused by Conidiobolus coronatus or related species

a. Zygomycota
b. Cunninghamella
c. Rhino-entomophthotomycosis
d. Rhizopus

A

c

57
Q

Paranasal sinuses inhalation of sporangiospores

a. Rhinocerebral zygomycosis
b. Gastrointestinal zygomycosis

A

a

58
Q

Associated with severe malnutrition, Gastrointestinal diseases

Present in necrotic ulcers

a. Rhinocerebral zygomycosis
b. Gastrointestinal zygomycosis

A

b

59
Q

Clinical material for zygomycetes are:
Skin scraping
Sputum
Nasal discharge
Aspirates from sinuses
Tissue Biopsy

T or F

A

T

60
Q

In microscopy

→ Broad, infrequently septate, thin-walled hyphae
→ Show focal bulbous dilations and irregular branching

a. zygomycetes
b. lobomycetes

A

a

61
Q

Zygomycosis has no serology test

T or F

A

T

62
Q

Lacazia loboi

Also known as Lobo’s disease or lacaziosis

a. zygomycosis
b. lobomycosis

A

b

63
Q

This disease is usually found in humans and bottle-nosed DOLPHINS

a. zygomycosis
b. lobomycosis

A

b

64
Q

Clinical material for lobomycosis is only surgical biopsy

T or F

A

T

65
Q

Direct microscopy: 10% KOH and Parker ink and Calcofluor white for Lobomycosis

T or F

A

T