6 - The Liver and Metabolic Homeostasis Flashcards
liver lobules
basic functional units of the liver
Kupffer cells
macrophages in the liver
bile formation
- Comprised of water, bile salts, bilirubin, and cholesterol
- Bile salts help absorb dietary fats and fat-soluble vitamins from the small intestine (95% are returned to the liver through the hepatic portal vein)
bile salts
compounds in bile that aid in emulsification
bile pigments
waste products from the breakdown of haem group of haemoglobin
what colour is bilirubin?
yellow
Functions of the liver
bile production, storage, nutrient interconversion, detoxification, phagocytosis, synthesis
Glycogenesis
glucose to glycogen
Glycogenolysis
breakdown of glycogen to glucose
Gluconeogenesis
formation of glucose from noncarbohydrate sources
Lipolysis in postabsorptive state
adipocytes release fatty acids into blood
Lipogenesis in absorptive state
stores triglycerides in adipocytes and hepatocytes
Catabolism
Metabolic pathways that break down molecules, releasing energy.
Anabolism
Metabolic pathways that construct molecules, requiring energy.