6. Bacterial Genetics and Pathogenicity Flashcards
Gene
A segment of DNA that specifies for a particular polypeptide
Codon
a sequence of three nucleotides which together form a unit of genetic code in a DNA or RNA molecule.
Non-sense codon
UAA, UGA and UAG do not code for any amino acid; stop codons. Terminate synthesis of polypeptide.
DNA
- 4 nucleic acid bases: purine (Adenine, Guanine) & pyrimidine (Cytosine, Thymine)
- Backbone: deoxyribose phosphate
- strands held together by hydrogen bond
RNA
- One chain of nucleotides
- sugar ribose instead deoxyribose
- Uracil instead of thymine
Types of RNA
- Messenger RNA
- Ribosomal RNA
- Transfer RNA
Messenger RNA (mRNA)
A type of RNA that carries the code or chemical blueprint for a specific protein
Ribosomal RNA (rRNA)
A nucleic acid plays a role in transferring information from DNA to the protein-forming system of the cell
Transfer RNA (tRNA)
Short-chain RNA that attach the correct amino acid to the protein chain that is being synthesized at the ribosome of the cell.
Extra chromosomal genetic elements
- Plasmid(s)
- Bacteriophage or prophage
- Transposon
Plasmid
- Circular DNA molecules present in the cytoplasm of the bacteria
- Encode genetic information for many properties
Types of plasmids
- Conjugative plasmids (F plasmids & R plasmids)
2. Non-conjugative plasmids