5.4 Active transport Flashcards
What is active transport
The movement of particles across a plasma membrane against a concentration gradient requiring metabolic energy
Describe Active transport across a membrane using a carrier proteins
Molecule binds to specific complementary receptor on carrier protein
On inside of cell, ATP binds to carrier protein, hydrolysed ⟶ ADP + Pi
Phosphate binds to carrier protein, causes conformational change.
Molecule released into cell.
Phosphate released from carrier protein, phosphorylates ADP & causes carrier protein to return to original shape.
What is bulk transport
Form of active transport
where large molecules or whole bacterial cells
are moved in/out of cells by exocytosis/endocytosis
Describe endocytosis and exocytosis
ENDOCYTOSIS - bulk transport of material into cell by invagination of plasma membrane, forming vesicle
Phagocytosis (solids), pinocytosis (liquids)
EXOCYTOSIS - bulk transport of material out of cell by fusion of vesicles with plasma membrane & release of contents
What causes the conformational change in shape of carrier proteins during active transport?
Binding of phosphate to carrier protein after ATP binds to carrier protein & is hydrolysed
What’s phagocytosis
endocytosis of solid material