5 - Testicular Cancer

Question 1

What is the most common SOLID malignancy affecting young males?

Answer 1

testicular cancer

Question 2

Cryptochordism is a risk factor what type of cancer?

Answer 2

testicular cancer

Question 3

What is the treatment for cryptochordism and what is it necessary?

Answer 3

• early orchiopexy (<2 years old)

- can lead to infertility and cancer

Question 4

Painless swelling or nodule in one testicle should have you concerned for this cancer.

Answer 4

testicular cancer

Question 5

The majority of testicular cancer (90%) are from what cells?

Answer 5

germ cell tumors

Question 6

What are the 2 distinguishing factors when trying to figure out if the testicular cancer is a seminoma or non-seminoma?

Answer 6

• seminoma is SLOW growing AND occurs commonly in men in their 40s (older)

Question 7

On scrotal ultrasound, well defined hypoechoic lesions w/o cystic areas is consistent with what type of testicular cancer (seminoma vs. non-seminoma)

Answer 7

seminoma

Question 8

What is the most common testicular cancer of children (infants)?

Answer 8

yolk sac non-seminomas

Question 9

What are the 3 serum tumor markers that have a role in management of testicular germ cell tumors?

Answer 9

• b-HCG
• AFP
• LDH

Question 10

What serum tumor marker is the most commonly elevated marker in nonseminomatous germ cell tumors?

Answer 10

• b-HCG

Question 11

What is the only reliable method to identify nodal micrometasteses?

Answer 11

• retroperitoneal lymph node dissection

Question 12

What is the mainstay of treatment for any type of testicular cancer?

Answer 12

orchiectomy

+/- radiation
+/- chemo