5- mitotic cell cycle Flashcards
Importance of mitosis:
Growth of multicellular organisms: production of genetically identical cells ensures all new cells have same genetic material as original, maintaining organism’s characteristics
Replacement of dead/damaged cells: ensures functionality of tissues maintained without altering DNA composition
Tissue repair by cell replacement
Asexual reproduction: organisms reproduce without need for gametes/fertilisation. Produces offspring genetically identical to parent, ensuring survival in stable environments
Telomeres:
repetitive sequences of non-coding DNA found at ends of eukaryotic chromosomes
Role of telomeres:
- prevent loss of genes during division
- allow continued cell division
- prevent shortening of chromosomes
When are chromatids formed?
during the interphase of the replication of the DNA strand.
prophase
- chromosomes condense+become visible
- nuclear envelope breaks down, nucleolus disappears
- centrioles move to opposite poles of cell
metaphase
chromosomes line up on equator of cell + centromeres attach to spindle fibres
anaphase
chromatids continue moving to opposite poles, centromeres first and
- they are pulled by the shortening of the microtubules
telophase
chromatids reach opposite poles of cell+uncoil.
nuclear envelope forms around each chromosome set+nucleoli form
cytokinesis
cytoplasm divides to form 2 new daughter cells
how can cancer drugs prevent mutations occuring
prevent DNA replication in interphase
interfere with formation of spindle fibres in prophase
stem cell features
divide by mitosis to form more cells
differentiate into diff types of specialised cell
types of stem cell:
- embryonic=pluripotent, can differentiate into any type of cell
- adult=multipotent. responsible for tissue+repair
- totipotent=embryonic(placenta) can develop into any organism
Toti
diff into any type of cell+produce whole organisms
pluri
most cell types, but not produce whole organisms
multi
few cell types, growth+repair
meristem
plant tissue continually growing+contain stem cells