11- immunity Flashcards
specific response includes
cellular response
humoral response
cellular
T lymphs respond to antigens presented on body cells
humoral
B lymphs where they produce antibodies in body fluids
T helper
- receptors on CSM binding to complementary antigens on APCs
produce interleukins(cytokine) stimulating B cells/phagocytes
(can form killer/memory)
T-killer
kill foreign/abnormal cells by producing perforin
makes holes in CSM-> becomes freely permeable to water, causes cell death
T memory
long term immunity
humoral response
use of B lymphocytes producing antibodies
B cells
have antibodies on CSM binding to complementary antigens
engulf antigens+APC
once activated(receptor binds), divide into plasma+memory
plasma cells
B cells that produce+secrete antibodies against specific antigen
short lifespan of few days
memory cells
B cell providing long term immunity against specific pathogen- longer lifespan
rapidly divide into plasma cells if body re-infected by same pathogen
helper T cells
bind to APC to activate division of B cells
Clonal SELECTION
B cell with the correct antibody is selected for cloning (by being activated by a T helper cell)
Clonal EXPANSION
DIVISION of specific B cells to produce genetically identical clones