5. Development Of The Heart & Great Vesssels Flashcards
What is the worldwide incidence of congenital heart defects ?
1% of live births
What percentage of people with congenital heart defects survive until adulthood ?
90%
Are medications used to treat heart disease teratogenic?
Yes, highly
What is the most common cause of indirect maternal death ?
Congenital heart defect
What are the zones of the primitive heart tube in direction of blood flow?
Sinus venosus Primitive atrium Primitive ventricle Bulbus cordis Truncus arteriosius Aortic roots
Why is the right atrium rough ?
Because it is mainly derived from the primitive atrium (which is rough trabeculated tissue)
Why is the left atrium smooth ?
Because it is mainly derived from the proximal primitive pulmonary vein (which is a vessel..so smooth!)
Which embryonic tissue is the right atrium mainly derived from ?
Primitive atrium
Which embryonic tissue is the left atrium mainly derived from ?
Proximal Primitive pulmonary vein
Once developed Which atrium has a rough trabeculated wall?
Right atrium
Where does gas exchange happen in a foetus ?
Placenta
What are two differences between foetus and mature circulatory system ?
- Foetus lungs do not exchange gas
- Foetus circulatory system requires shunts to move move to right place.
How many shunts are there in the foetus?
3
What is the shunt at the right atrium called ?
Foramen ovale
What is the shunt at the lung called ?
Ductus venosus
What is the shunt at the pulmonary trunk called?
Ductus arteriosus
What is the remnant of ductus arteriosus ?
Ligamentum arteriosum
Where does foramen ovale shunt blood from and to?
RA -LA