5 Flashcards
what are cancer cells, how do they form and how do cancer cells spread
unspecalised cells that divide and grow rapidly unctrollable to form a tumour
cancer cells form to genetic changes when a normal cell is transformed into a malignant cell
cancer cells spread by dividing uncontrollably and spreading to surrounding tissues.
An example of an essiental change that causes magliancy
failure in apoptosis
a cell infected by a virus can be secreted by
apoptosis if a natural killer cell finds it early enough to destroy and necrosis if the cell goes unchecked for a while
apoptotic cells are characterised by and what occurs after apoptosis and what can a failure in apoptosis lead to
A
cell shrinkage, blebbing, condensation of chromatin and fragmentation of DNA nad nucleus
phagocytosis occurs after apoptosis
failure in apoptosis can lead to cancer
signal transduction
the process of transferring a signal throughout an organism
function of capscase 3
breaks down cytokseleton
process death receptor pathway
Caspase enzymes are activated
Organelles begin to breakdown
The cell and nucleus shrinks
Blebbing of the plasma membrane occurs forming apoptotic bodies
Apoptotic bodies are engulfed by phagocytes (immune cell).
After caspase enzymes are activated, what happens
cell shrinks/collaspes
DNA condenses and fragments
Blebbing
apopotic bodies break away and phagocytosis occurs
stem cell therapy
promotes the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. It
steps of embyro development
Fertilization → Zygote → Cleavage → Morula → Blastula → Gastrula.
Extrinsic factors of apoptosis vs instrinsic factors of apoptosiis
Extrinsic factors of apoptosis are mild cell injury or damage to cell membrane
Instrinsic factors of apopotsis are viral infections or DNA damage
Q
The number of cancer cells within the tissue is
rapidly increasing. This increase in the number
of cancer cells can be explained by
impaired signalling from death receptors located on the membrane of the cancer cells.
descending limb is only permable to
water
what is the ascending limb permeable to
salt
how does the nephron filter blood to produce urine
- filtration formation- blood is squeezed and filtered through the thin walls of the glomerulus into the bowmans capsuel as filtrate which contains water, glucose, ions and urea, whilst larger moleucles such as blood cells and proteins stay in the blood
2.selective reabsorption in the proximal convulted tubule-glucose, amino acids and ions are reabsorbed via active transport, whereas ammonia, creatinine and toxins are secreted into the tubule.
3.water leaves the filtrate by osmosis in the descending limb and salt leaves the filtrate in the ascenidng limb.
4.water reabsorption in the loop of henle, filtrate empties into the collecting duct to create concentrated urine
5.After being produced in the kidneys, the filtrate, now called urine, leaves the kidneys via a tube called a ureter. The ureter carries the urine to the bladder. When ready to be emptied, urine passes out of the urethra.