4th Year Non-Melanoma Cancer Flashcards
RF for development of skin cancer
immunosuppression sun damage outdoor job time spent abroad previous hx of cancer FH use of sunbeds skin types sunburn phototoxic drugs
classic appearance of BCC
rolled edge with central ulceration
telangiectasia
erodent ulcer
what cell forms a BCC?
basal keratinocytes
typical hx of BCC
slow growing
won’t quite heal
microerosions
scale
management of BCC
imiquimod/aldara
5-FU cream
radiotherapy
surgery
examples of pre-cursors for SCC
actinic keratosis
Bowen’s disease
describe appearance of Bowen’s disease
plaque on leg that is unchanging, asymptomatic, won’t go away
how deep is Bowen’s disease?
full thickness dysplasia (carcinoma in-situ)
which sites of SCC are more likely to behave aggressively?
ears and lips
what is a RF for SCC around the mouth?
smoking
management of SCC
efudix aldara topical diclofenac solaraze phototherapy cryotherapy surgery
what is Moh’s surgery?
staged resection of a lesion with immediate surgical margin examination to ensure clear margins whilst maximising conservation
indications for Moh’s
- location (mask area)
- size= >6mm
- poorly defined borders
- recurrent or incompletely excised lesions
- immunosuppression
- aggressive histological sub-type
follow-up arrangements for Moh’s surgery?
1 weeks
then 3 months
then 6 monthly
