Cutaneous Drug Eruptions

Question 1

define

Answer 1

dermatological presentation of a reaction to a drug

Question 2

when does this usually resolve?

Answer 2

when the drug is removed

Question 3

diagnosis

Answer 3

history and examination
biopsies
patch testing

Question 4

when is skin testing not indicated?

Answer 4

serum sickness reactions (type 3) or T-cell mediated reactions (types 4) as can trigger SJS, TEN and DRESS

Question 5

management

Answer 5

discontinue drug if possible
topical corticosteroids
antihistamines for type 1
allergy bracelet
yellow card scheme

Question 6

classification of cutaneous drug eruptions

Answer 6

1. immunological
2. non-immunological
3. exanthematous
4. urticarial
5. pustular or bullous
6. fixed
7. phototoxic