4.a Quality Assurance Flashcards
Analytical Sensitivity to Pooled Serum
Ability to detect small amounts of analyte
ANALYTICAL SENSITIVITY
Ability to detect only the analyte of interest
ANALYTICAL SPECIFICITY
Closeness of the value to the target/true value
ACCURACY
Closeness of the value to the repeated value
PRECISION
Ability to maintain both accuracy and precision
RELIABILITY
Indicator of precision
standard deviation
coefficient of variation
standard deviation
Relative indicator of precision
standard deviation
coefficient of variation
coefficient of variation
CV= (SD/mean) x 100
Lower coefficient of variation indicates:
GOOD or BAD PRECISION
GOOD PRECISION
Measures the statistical differences between 2 means
t-test
Measures the statistical differences between 2 SDs or 2 variances
F-test
bell-shaped curve; assumes that mean = median = mode
Gaussian curve
1sd (outside) =
31.7%
inside = 68.3%
2sd (inside) =
95.5%
3sd (inside) =
99.7%
Bull’s eye in the quality control chart indicates:
GOOD ACCURACY &
GOOD PRECISION
Type of QC where analysis of control samples together with patient specimen
INTRALAB/
INTERNAL QC
Control are materials of _ (known/unknown) value that is analyzed with patient samples to determine acceptability of results.
It is of known quality with several analytes present.
It resembles patient (serum/plasma) _.
Controls are usually made from (pooled plasma/pooled serum) _.
known value
patient serum
pooled serum
