43: Learning And Memory Flashcards
How do short term memory structures connect to the neocortex and amygdala?
Via the nucleus basalis of Meynert
What type of nts does the nucleus basalis of Meynert use? What disease process is it indicated in?
Cholinergic; Alzheimers
Where is spatial memory stored?
Hippocampus
Place cells
Special pyramidal cells in CA1
When do place cells fire?
When in specific places, especially if you got a reward there
Three cell types that send info to place cells
- Grid cells
- Head direction cells
- Border neurons
Grid cells
Create a grid map of place you are in (triangular or hexagonal
Location in brain of grid cells
Entorhinal cortex
Border neurons
Fire when near a border or wall
Head direction cells
Tell you what direction your head was pointing to see an area
Basis of production of memory and learning
Plasticity
Two ways to alter plasticity
Change synaptic function + change physical structure of neurons
Three ways to change structure of neurons
- Gain/lose synapses
- Structural changes in dendrites
- Structural changes in somas
Two ways to change synapstic functioning
- Post-tetanic potentiation
2. Long-term potentiation
What nts can be used in long-term potentiation?
The model is based on EAA, but can be seen with other nts too