410 Quiz#2 Flashcards
Components of BMP
- sodium, potassium, chloride, bicarbonate/CO2, BUN, creatinine and glucose
Factors Affecting GFR
- Age: GFR decreases with age
- Gender: GFR is lower in female
- Race: higher GFR used to be accepted in black patients
Gross Assessment of Urine
turbidity, Color, and smell
Urine Dipstick
- specific gravity: urince concentration
- pH: reflects serum pH
- RBCs
- protein: proteinuria = hallmark of renal disease
- glucose: when blood glucose > 180mg/dL
- Ketones: not normally in urine; byproduct of fat metabolism, uncontrolled DM
- bilirubin: conjugated bilirubin, screens for liver or bile duct disease
RBCs on urine Microscopy
- hematuria: >3RBCs per HPF
- gross color can be misleading
- transient vs persistent (persistent requires work-up)
- dysmorphia indicates glomerular disease
WBCs on urine microscopy
- Pyuria: >5 WBCs per HPF
- neutrophils: bacteria, renal TB, lithiasis
- Eosinophils: interstitial nephritis
Epithelial Cells on Urine Microscopy
- shed from genitourinary tract
- excess of epithelial cells may indicate contamination
- renal disease/tubular disease: >15 epithelial cells per 10HPF
Nitrates vs Nitrites
- Nitrate: normal constituent of urine; converts to nitrite in presence of certain bacteria
- Nitrites: abnormal, correlate well with possible infection; >10,000 bacteria count per mL
Leukocyte Esterase
enzyme produced by neutrophils, signals pyuria
subject to contaminated specimen, read only after 30-60 secs
nonspecific: TB, tumors, viral, stones, foreign bodies
works with synovial fluid as well to test for septic joint
Accuracy of hematuria, leukocytosis, and nitrites in urinalysis
- hematuria: very sensitive but not specific
- leukocytosis: very sensitive, not specific
- Nitries: not sensitive, very specific
Myocardial Cells
- “working cells” of the heart, contractile ability
- connected by intercalated discs with gap junctions
- held to by desmosomes
When Heart Cells are injured they release:
Troponin and CPK-MB
Anterior Leads
V1-V4
Lateral Leads
V5-V6, aVL, lead I
Inferior Leads
aVF, lead II, and lead III
Normal Intervals
PR: 0.12-0.20s
QRS: 0.06-0.11s
QT: 0.36-0.44s
ECG paper
small square: 0.04 s in duration, and 0.1mV in amplitude
P wave
- normal duration: 0.06-0.10s; Amplitude: 0.5-2.5mm
- if amplitude >2.5mm = RAE, P pulmonale
- if duration > 0.10s (2.5 boxes) = LAE, P mitrale
Flutter Waves
- seen instead of normal P waves when the atria fire rapidly from one site at a rate of 250-350bpm “Saw tooth pattern”
Fibrillatory Waves
seen instead of P waves when the atra fire rapidly from many sites at a rate of >350bpm
Short QRS complexes (in amplitude)
obesity, hypothyroid patients, pericardial effusion
1st degree AV heart block
when the PR interval is lengthened consistently due to a delay in impulse conduction through the AV node
2nd degree AV heart block
- PR intervals get progressively longer until a QRS complex is skipped and the cycle repeats