4.1 study guide Flashcards
What did Griffith call one strain of bacteria acquiring a factor from another bacteria?
Transformation
Avery, McLeod, and McCartney wanted to figure out what?
If DNA or proteins were the transforming factors. Turned out to be DNA.
What did Hershey and Chase do?
Experimented with viruses. Concluded that DNA was still the transforming factor.
What was Chargoff responsible for?
A=T
G=C
Adenine pairs with what base?
thymine
Guanine pairs with what base?
cytosine
What 2 bases are pyrimidines?
T and C
What 2 bases are purines?
A and G
What is a pyrimidine?
1 ring
What is a purine?
2 rings
What type of bond holds the 2 strands together?
hydrogen bonds
What type of bond holds the nucleotide together to create the sugar/phosphate backbone?
covalent phosphodiesterase bonds
5 prime is attached to what group?
phosphate
3 prime is attached to what group?
hydroxyl
DNA runs
anti parallel