4 Part 1: Pertechnetate Flashcards
what is the oxidation state of the Tc atom?
-1 to +7
when SC is binding to Tc, what is the oxidation state of Tc?
+7
central metal cation
Tc + surrounded by oxygen atoms
where does localization of Tc occur (within first hour)?
gastric mucosa, thyroid, salivary glands
how does Tc get excreted?
primarily through the kidneys over the first 24 hours, then the bowels after that
critical organ of Tc
large bowel
what are the two main patient uses of pertechnetate?
- thyroid scan
- meckel’s scan (gastric mucosa)
__ % accumulates an hour from injection in the thyroid
__ % accumulates an hour from injection in the stomach
thyroid - 2%
stomach - 20%
dose needed for a thyroid scan
74-370 MBq IV
dose needed for an ectopic gastric mucosa
in adults:
370-555 MBq IV
kids:
7.4-11.1 MBq/kg