4 Pain and Temperature - A Flashcards
Name 2 main tracts that are motor and descending pathways?
- Pyramidal tracts
- Extrapyramidal tracts
What are the sub-tracts of Pyramidal tracts? (2)
- Lateral corticospinal tract
- Anterior corticospinal tract
What are the sub-tracts of Extrapyramidal tracts? (4)
- Rubrospinal tract
- Reticulospinal tract
- Olivospinal tract
- Vestibulospinal tract
Name the 3 main tracts of sensory and ascending (afferent) pathways?
- Dorsal Column Medial Lemniscus System
- Spinocerebellar tracts
- Anterolateral system
What are the sub-tracts of Dorsal Column Medial Lemniscus system? (2)
- Gracile fasciculus
- Cuneate fasciculus
What are the sub-tracts of the Spinocerebellar tracts? (2)
- Posterior spinocerebellar tract
- Anterior spinocerebellar tract
What are the sub-tracts of the Anterolateral system? (2)
- Lateral spinothalamic tract
- Anterior spinothalamic tract
What pathway are rapid, sharp, pricking, precise localized pain and temperature conveyed via?
direct spinothalamic (“fast” pain) pathway
What are the two types of fibers that are part of the direct spinothalamic (“fast” pain) pathway?
- A-delta fibers
- C fibers
Describe A-delta fibers.
myelinated with conduction rate (5-30 m/s)
Describe C fibers.
unmyelinated with conduction rate (0.5-2 m/s)
How are burning, throbbing, dull, aching, diffuse pain AND crude touch/pressure conveyed via?
indirect spinothalamic system (“slow” pain pathway)
What fibers make up the indirect spinothalamic system (“slow” pain pathway)?
C fibers
Describe the direct spinothalamic (“fast” pain) pathway.
receptor –> spinal cord –> lateral thalamus –> somatosensory cortices
Describe the indirect spinothalamic system (“slow” pain pathway).
receptor –> spinal cord –> reticular formation –> medial thalamus –> cingulate, frontal, limbic cortices
Primary neurons of the direct spinothalamic (“fast” pain) pathway start where?
- peripheral pain/temperature receptors.
Primary neurons of the direct spinothalamic (“fast” pain) pathway enter the spinal cord where ascend/descend via what tract?
- Fibers enter the spinal cord through the dorsal root ganglion and ascend/descend (1-2 segments) in the posterolateral fasciculus (Lissauer’s tract)
Primary neurons of the direct spinothalamic (“fast” pain) pathway terminate on 2nd order neurons where?
- Fibers then synapse on the secondary neurons in the substantia gelatinosa and some synapse in the nucleus proprius
Secondary neurons of the direct spinothalamic (“fast” pain) pathway start where and cross via ___ to enter which part of the anteriolateral/spinothalamic tract?
- the substantia gelatinosa/(nucleus proprius) cross in the anterior white commissure (AWC) and ascend in the Lateral spinothalamic Tract (LSTT) of the contralateral anterolateral funiculus
Secondary neurons of the direct spinothalamic (“fast” pain) pathway organize themselves how in the LSTT?
-
Somatotopic lamination of the Lateral Spinothalamic Tract (LSTT).
* Sacral* levels enter the tract first and are located in the posterolateral aspect of the tract
* Cervical* levels enter the tract last and are located in the anteromedial aspect of the tract
Secondary neurons of the direct spinothalamic (“fast” pain) ascend through spinal cord via what tract(s) and terminate where?
- In the medulla, the Lateral Spinothalamic Tract (LSTT) joins with the Ventral Spinothalamic Tract (VSTT) and spinotectal tract to form the spinal lemniscus (SL). The SL terminates in the Ventral Posterior Lateral (VPL) nucleus of the dorsal thalamus
Describe what you would see with a patient with Brown-Sequard Syndrome.
HEMISECTION OF SPINAL CORD
- Loss of Pain and temp from contralateral side of body
- complete loss of pain and temperature sensation 1-2 levels below level of lesion (Lissauer’s tract)
- Loss of Discriminative touch and conscious proprioception on ipsilateral side below
- ipsilateral loss of ALL sensation at level
- motor loss
What is Syringomyelia?
Formation of fluid filled cyst (syrinx) within the spinal cord (within central canal), most common C8-T1
- Pain and temperature affected
Anterior white commissure (2nd order fibers of spinothalamic tract affected)
- Results in bilateral loss of pain/temperature sensation in shawl or cape-like distribution
- Motor also lost if the cyst expands into anterior horn
Describe the normal bladder reflex.
Mechanoreceptors in bladder wall (detrusor muscle) are stretched when bladder fills. Impulses are sent to S2-S4 via visceral afferent innervation (pelvic nerve) and enter the dorsal root to synapse on visceral afferent nucleus. Interneurons convey stimulus to sacral autonomic nucleus. Visceral efferent neurons from SAN will cause the detrusor to contract and internal sphincter to relax.
Signals also sent from visceral afferents to pontine micturition center (PMC) which can override the micturition reflex OR increase the reflex depending on current situation (is it okay to urinate?)
When micturition is desired, PMC increases impulses via pelvic nerve (efferent) causing contraction of detrusor muscle. Also, somatic innervation via pudendal nerve to external sphincter is inhibited causing relaxation and micturition.
What lesions cause Atonic Bladder
dorsal roots of S2-S4
What is seen clinically due to Atonic Bladder.
(Remember lesions at dorsal roots of S2-S4)
Micturition reflex contraction cannot occur if the sensory nerve fibers from the bladder to the spinal cord are destroyed, thereby preventing transmission of stretch signals from the bladder
Instead of emptying periodically, the bladder fills to capacity and overflows a few drops at a time through the urethra. This is known as overflow incontinence.
What spinal cord damage is seen with reflex/automatic bladder?
Spinal cord damage above the sacral region (S2)
