4: GENETICS - DNA, GENES AND CHROMOSOMES Flashcards

1
Q

How is DNA stored in eukaryotic cells?

A
  • wound around histone proteins
  • DNA with proteins coiled up repeatedly to form chromosomes
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2
Q

How is DNA stored in mitochondria and chloroplasts?

A

circular chromosomes (similar to prokaryotic DNA)

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3
Q

How is DNA stored in prokaryotic cells?

A
  • shorter, circular chromosomes
  • DNA condenses to fit in the cell by supercoiling
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4
Q

Compare the structure and organisation of eukaryotic and prokaryotic DNA (4 marks)

A
  • eukaryotic - very long, linear DNA molecules​
  • prokaryotic - short, circular DNA molecules
  • eukaryotic - DNA associated proteins ​
    called histones, DNA wound around histones, then coiled tightly to make compact chromosome that are located in nucleus
    ​- prokaryotic – no associated proteins , DNA condenses by supercoiling ​into chromosome
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5
Q

What is a gene?

A

a sequence of DNA bases that codes for a polypeptide/functional RNA

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6
Q

What determines the order of amino acids in a particular polypeptide?

A

the order of bases in a gene

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7
Q

How many bases code for 1 amino acid?

A

3

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8
Q

What is the name of the sequence of bases in a gene that code for an amino acid?

A

a DNA triplet

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9
Q

What is functional RNA?

A

RNA molecules other than mRNA and rRNA

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10
Q

What is genome?

A

the complete set of genes in a cell

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11
Q

What is proteome?

A

the full range of proteins that a cell is able to produce

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12
Q

What are sections of DNA that don’t code for amino acids called?

A

introns

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13
Q

Do eukaryotic cells have introns?

A

yes

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14
Q

Do prokaryotic cells have introns?

A

no

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15
Q

What are sections of DNA that do code for amino acids called?

A

exons

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16
Q

What is an allele?

A

a different form of a gene that codes for a slightly different version of the same polypeptide

17
Q

How many chromosomes do humans have and how many pairs?

A
  • 46 chromosomes
  • 23 pairs
18
Q

What is a homologous pair of chromosomes?

A

a pair of matching chromosomes

19
Q

What is a locus?

A

the fixed position that a gene occupies on a particular chromosome

20
Q

What are the features of homologous chromosomes?

A
  • same size
  • alleles at the same locus
  • different alleles