4- Energy And Fats Flashcards

0
Q

How many fatty acids and how many glycerol molecules do triglycerides contain?

A

3 fatty acid molecules and one glycerol molecule

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1
Q

What are the 3 types of lipids?

A

Triglycerides, phospholipids, sterols

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2
Q

What are fatty acids classified by?

A
  1. Carbon chain length
  2. Saturation level
  3. Shape
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3
Q

How are trans fats produced?

A

Hydrogenation - hydrogen atoms added to unsaturated fatty acids, making oils more solid and saturated.

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4
Q

What are the 2 essential fatty acids?

What are they precursors to?

A

> Linoleic acid (omega 6) found in veg oil and nuts
Alpha linoleic acid (omega 3) in fish
Precursers to eicosanoids

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5
Q

What are the 2 essential fatty acids?

What are they precursors to?

A

> Linoleic acid (omega 6) found in veg oil and nuts
Alpha linoleic acid (omega 3) in fish
Precursers to eicosanoids (prostaglandins, thromboxanes, leukotreines)

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6
Q

What do omega 3 fatty acids stimulate?

A

Release of prostaglandins, thromboxane and
Leukotriene

These reduce inflammatory responses and blood clotting.

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7
Q

What are phospholipids made of? What do they do?

A

Glycerol backbone, 2 fatty acids, phosphate.

Soluble in water and transport fat into the bloodstream.

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8
Q

What are sterols and what do they do in the body?

A

Multiple rings of carbon atoms with an OH group

Plant sterols appear to block absorption of dietary cholesterol

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9
Q

____ transport lipid digestion products (___,___,___,___) to the ____ of the small intestine for absorption.

A

Micelles
( cholesterol, cholesterol ester, free fatty acid, monoacylglyceride)
Enterocytes

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10
Q

What makes the gallbladder contract in digestion of dietary fats?

A

Secretion of cholecystokinin (CCK) and secretin from the duodenal mucosal cells

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11
Q

What are chylomicrons and what do they do?

A

Lipoproteins
Transport lipids from enterocyte to lymph system for absorption into bloodstream
Composed of fatty acids surrounded by phospholipids and proteins

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12
Q

Where are VLDLs formed and what do they do?

A

80% in the liver and 20% in the intestine

Transport endogenous lipids, especially triglycerides to the various tissues of the body

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13
Q

Where are LDLs formed and what do they do?

A

In the blood from VLDLS (removal of of triglycerides)

Transports cholesterol to cells of the body

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14
Q

Where are HDLs formed and what do they do?

A

Synthesised in the liver and released into the blood

Transports cholesterol from tissues back to the liver

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15
Q

What is the predominant polyunsaturated fatty acid brain phospholipid?

A

Docosahexaenoic acid

16
Q

What are Eicosanoids/icosanoids?

A

Signaling molecules made by oxidation of 20-carbon fatty acids.
Derived from either omega-3 (ω-3) or omega-6 (ω-6) fatty acids. In general, the ω-6 eicosanoids are pro-inflammatory; ω-3s are much less so.
Anti-inflammatory drugs such as aspirin and other NSAIDs act by downregulating eicosanoid synthesis.

17
Q

What are Eicosanoids/icosanoids?

A

Signaling molecules made by oxidation of 20-carbon fatty acids.
Derived from either omega-3 (ω-3) or omega-6 (ω-6) fatty acids.
ω-6 eicosanoids are pro-inflammatory; ω-3s are much less so.
Anti-inflammatory drugs such as aspirin and other NSAIDs act by downregulating eicosanoid synthesis.