4/26 Lecture E2 Flashcards
In what ways is the urinary system closely associated with the reproductive system?
1) shared embryonic development and adult anatomical relationship
2) collectively called the urogenital (UG) system
What are the functions of the kidneys? (8)
1) Filter blood and excrete toxic metabolic wastes
2) Regulate blood volume, pressure, and osmolarity
3) Regulate electrolytes and acid-base balance
4) secrete erythropoietin
5) help regulate calcium levels by participating in calcitriol synthesis
6) clear hormones from blood
7) detoxify free radicals
8) in starvation, synthesize glucose from amino acids
What is waste?
Any substance that is useless to the body or present in excess of the body’s needs
What is metabolic waste?
waste substance produced by the body
What are the steps in urea formation?
Proteins –> amino acids –> NH2 removed –> forms ammonia
What organ converts ammonia to urea?
the liver
What is uric acid a product of?
nucleic acid catabolism
What is creatinine a product of?
creatine phosphate catabolism
What is Blood Urea Nitrogen (BUN)?
The level of nitrogenous waste in the blood
What is the normal concentration of blood urea?
10-20 mg/dL
What does Azotemia mean?
elevated BUN
What does azotemia indicate?
renal insufficiency
What are the symptoms of uremia?
diarrhea, vomiting, dyspnea, weakness, and metabolic acidosis.
What does uremia stem from?
toxicity of nitrogenous waste
What is the treatment for uremia?
hemodialysis or organ transplant
What is excretion?
separating wastes from body fluids and eliminating them
What are the four body systems that carry out excretion?
1) respiratory system
2) integumentary system
3) digestive system
4) urinary system
What does the respiratory system excrete?
CO2, small amounts of other gases, water
What does the integumentary system excrete?
water, inorganic salts, lactic acid, and urea (in sweat)
What does the digestive system excrete?
water, salts, CO2, lipids, bile pigments, cholesterol, and other metabolic waste
What does the urinary system excrete?
many metabolic wastes, toxins, drugs, hormones, salts, H+, and water
Where is the kidney located?
posterior abdominal wall at level of T12 to L3
Why is the right kidney slightly lower?
Due to the large right lobe of liver
What rib crosses the middle of the left kidney?
Rib 12
T of F: the kidney, ureters, urinary bladder, renal artery and vein, and adrenal glands are all retroperitoneal
T
What is Murphy’s punch/sign
thoracic spine examination testing for kidney inflammation, infection and obstruction
What is the shape and size of a kidney comparable to?
the size of your fist, lateral convex surface and medial concave surface with a slit (hilum)
What does the hilum receive?
renal nerves, blood vessels, lymphatics, and ureter
What are the three protective tissue coverings around the kidney?
1) Renal fascia
2) Perirenal fat capsule
3) Fibrous capsule
What is the role of the renal fascia?
binds the kidney to the abdominal wall
What is the role of the perirenal fat capsule?
cushions the kidney and holds it into place
What is the role of the fibrous capsule?
encloses the kidney and holds it into place
How does the fibrous capsule connect to the renal fascia?
through collagen fibers
What is the renal parenchyma?
glandular tissue that forms urine
Shape and location of the renal parenchyma.
C-shaped in frontal section
What is the renal sinus?
cavity that contains blood and lymphatic vessels, nerves, and urine-collecting structures