4

Question 1

norethindrone acetate

Answer 1

progesterone

i: contraceptive, fertility need, amenorrhea
ta: progesterone-like effect
ci: tobacco use (clot), hepatic dysfx, thromboembolic hx, idiopathic vaginal bleed, PID, endometriosis, preg
c: cardiac hx, renal dysfx, asthma, epilepsy, migraine
ae: AE r/t admin route, systemic progesterone effect
di: barbiturate, rifampin, tetracycline, phenytoin, carbamazepine, penicillin, SJW all dec
ni: x

Question 2

raloxifene

Answer 2

estrogen receptor modulator

i: antineoplastic agent for breast cancer, dec postmenopausal breast cancer risk, prevent/tx osteoporosis
ta: selectively stimulate/block estrogen receptor site, inc bone mineral density
ci: preg/lact
c: tobacco use, thromboembolic hx
ae: GI, fluid change, thromboembolism, estrogen stimulating effect
di: cholestyramine and protein bound med dec, warfarin dec prothrombin time
ni: x

Question 3

clomiphene

Answer 3

fertility drug

i: female infertility w/ functioning ovary / IVF
ta: stimulate multiple follicle to grow egg
ci: ovarian failure, ovarian cyst, thyroid/adrenal dysfx, idiopathic uterine bleed, preg
c: respiratory dz, thromboembolic, lact
ae: HA, N/V, multiple preg risk, birth defect, abd pain/distension/bloating, fluid retention, uterine bleed, breast tenderness, ovarian stimulation (cyst)
di: x
ni: emotional support, education SQ injection, baseline exams