1

Question 1

Lorazepam

Answer 1

benzodiazepam

i: alcohol withdrawal seizure
ta: potentiate GABA, highly protein bound crosses BBB rapidly
ci: x
c: x
ae: x
di: x
ni: x

Question 2

clonazepam

Answer 2

benzodiazepam

i: absence seizure when succinimide fails
ta: potentiate GABA
ci: x
c: x
ae: inc salivation
di: x
ni: x

Question 3

ethosuximide

Answer 3

succinimide

i: absence seizure
ta: dec calcium influx, suppress abnormal activity
ci: x
c: renal/hepatic dz, preg/lact
ae: CNS depressant, BM suppression, pancytopenia, derm (SJS), SI
di: phenytoin dec, valproic acid dec
ni: children safe, monitor CBC b/c pancytopenia, CNS dep, and SJS