2

Question 1

valproic acid

Answer 1

seizure med

i: anti-seizure, migraine, mania
ta: block sodium channels, inc GABA
ci: sulfa/thiazide allergy, preg X / BBW - pancreatitis, teratogenic
c: x
ae: renal caliculi, hepatic fail, thrombocytopenia
di: phenobarbital, ethosuximide, diazepam, zidovudine
ni: monitor ammonia lv, inc fluid, BC

Question 2

carbamazepine

Answer 2

partial seizure med

i: partial seizure when other med didn’t work, migraine
ta: alter sodium/calcium channel, inc GABA
ci: severe hepatic dysfx, BM sup / BBW - aplastic anemia/agranulocytosis, SI
c: preg D
ae: CNS dep
di: MAOI (serotonin syndrome), inc dose warfarin, grapefruit
ni: taper dose, monitor CBC

Question 3

gabapentin neurotin

Answer 3

partial seizure med

i: partial seizure, neuropathic pain, migraine
ta: x
ci: x
c: x
ae: CNS dep, children behavior issue
di: x
ni: PO