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3SQ2 Flashcards

1
Q

Baclofen is a receptor agonist of which of the following?

a. Glycine
b. Opioid peptides
c. GABA
d. Endocannabinoids

A

c. GABA

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2
Q

WHich has an NMDA receptor subtype?

a. Acetylcholine
b. Dopamine
c. Glutamate
d. Norepinephrine

A

c. Glutamate

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3
Q

Which depletes monoamine synapses of transmitters by interfering with intracellular storage?

a. Amphetamine
b. Tetanus toxin
c. Cocaine
d. Reserpine

A

d. Reserpine

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4
Q

Type of voltage-gated ion channel receptor of Omage conotoxin

a. Potassium
b. Sodium
c. Calcium
d. None of the choices

A

c. Calcium

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5
Q

This blocks GABA-A channels

a. Batrachotoxin
b. Apamin
c. Picrotoxin
d. Omega conotoxin

A

c. Picrotoxin

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6
Q

System major excitatory neurotransmitters are aspartate and glutamate

a. hierarchical
b. non-specific or diffuse
c. both
d. neither

A

a. hierarchical

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7
Q

Neuronal system of adrenergic (NE) pathways

a. hierarchical
b. non-specific or diffuse
c. both
d. neither

A

b. non-specific or diffuse

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8
Q

Na channels that are highly concentrated on the axon hillock

a. Voltage gated-ion channels
b. Ligand gated-ion channels
c. Metabotropic receptors

A

a. Voltage gated-ion channels

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9
Q

Depends on secondary messengers to mediate intracellular signaling cascade

a. Voltage gated-ion channels
b. Ligand gated-ion channels
c. Metabotropic receptors

A

c. Metabotropic receptors

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10
Q

Glycine

a. inhibitory
b. excitatory
c. both
d. neither

A

a. inhibitory

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11
Q

histamine

a. inhibitory
b. excitatory
c. both
d. neither

A

c. both

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12
Q

opening of chloride channels

a. epsp
b. ipsp
c. both
d. neither

A

b. ipsp

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13
Q

depolarizing

a. epsp
b. ipsp
c. both
d. neither

A

a. epsp

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14
Q

increases membrane potential nearer the threshhold

a. epsp
b. ipsp
c. both
d. neither

A

b. ipsp

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15
Q

closing of potassium channels

a. epsp
b. ipsp
c. both
d. neither

A

a. epsp

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16
Q

glycine

a. amino acid
b. neuropeptides
c. monoamine
d. none of the given

A

a. amino acid

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17
Q

norepinephrine

a. amino acid
b. neuropeptides
c. monoamine
d. none of the given

A

c. monoamine

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18
Q

Anandamide is a receptor agonist of which of the ff:

a. glycine
b. opioid peptides
c. GABA
d. endocannabinoids

A

endocannabinoids

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19
Q

the best documented example of retrograde signaling

a. ketamine
b. methylxanthines
c. strychnine
d. opioids
d. endocannabinoids

A

d. endocannabinoids

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20
Q

which has a kainate receptor subtype

a. acetylcholine
b. dopamine
c. glutamate
d. norepinephrine

A

c. glutamate

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21
Q

Which can modify neurotransmitter responses mediated through cAMP

a. methylxanthines
b. strychnine
c. opioids
d. endocannabinoids

A

c. opioids

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22
Q

type of voltage-gated ion channel receptor of Agatoxin

a. Potassium channel
b. sodium channel
c. calcium channel
d. none of the choices

A

c. calcium channel

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23
Q

this is an irreversible nicotinic acetylcholine receptor antagonist

a. batrachotoxin
b. alpha-bungarotoxin
c. picrotoxin
d. omega conotoxin

A

b. alpha-bungarotoxin

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24
Q

include all the pathways directly involved in sensory perception and motor control

a. hierarchical
b. non-specific or diffuse
c. both
d. neither

A

a. hierarchical

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25
Q

neuronal system of serotonergic pathways

a. hierarchical
b. non-specific or diffuse
c. both
d. neither

A

b. non-specific or diffuse

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26
Q

can modulate voltage-gated channels via a membrane-delimited pathway

a. voltage-gated ion channels
b. ligand-gated ion channels
c. metabotropic receptors

A

c. metabotropic receptors

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27
Q

also known as ionotropic receptors

a. voltage-gated ion channels
b. ligand-gated ion channels
c. metabotropic receptors

A

b. ligand-gated ion channels

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28
Q

glutamate

a. inhibitory
b. excitatory
c. both
d. neither

A

b. excitatory

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29
Q

acetylcholine

a. inhibitory
b. excitatory
c. both
d. neither

A

c. both

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30
Q

opening of postsynaptic calcium channels

a. EPSP
b. IPSP
c. Both
d. Neither

A

a. EPSP

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31
Q

hyperpolarizing

a. EPSP
b. IPSP
c. Both
d. Neither

A

c. Both* (ipsp?)

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32
Q

GABA

a. amino acid
b. neuropeptides
c. monoamine
d. none of the given

A

a. amino acid

33
Q

histamine

a. amino acid
b. neuropeptides
c. monoamine
d. none of the given

A

c. monoamine

34
Q

Strychnine is a receptor antagonist of which of the ff:

a. GABA
b. Opioid peptides
c. Glycine
d. endocannabinoids

A

c. Glycine

35
Q

which of the following blocks the release of transmitters

a. amphetamine
b. tetanus toxin
c. capsaicin
d. cocaine

A

b. tetanus toxin

36
Q

type of voltage-gated ion channel receptor of tetrodotoxin

a. sodium channel
b. calcium channel
c. potassium channel
d. none of the choices

A

a. sodium channel

37
Q

this blocks “small Ca-activated” K channels

a. Apamin
b. batrachotoxin
c. charybdotoxin
d. omega conotoxin

38
Q

neuronal system of cholinergic (Ach) pathways

a. hierarchical
b. non-specific or diffuse
c. both
d. neither

A

b. non-specific or diffuse

39
Q

system which contain large myelinated, rapidly conducting fibers

a. hierarchical
b. non-specific or diffuse
c. both
d. neither

A

a. hierarchical

40
Q

these are responsible for fast synaptic transmission typical of hierarchical pathways

a. voltage-gated ion channels
b. ligand-gated ion channels
c. metabotropic receptors

A

b. ligand-gated ion channels

41
Q

these receptors respond to changes in membrane potential

a. voltage-gated ion channels
b. ligand-gated ion channels
c. metabotropic receptors

A

a. voltage-gated ion channels

42
Q

glycine

a. excitatory
b. inhibitory
c. both
d. neither

A

b. inhibitory

43
Q

histamine

a. excitatory
b. inhibitory
c. both
d. neither

44
Q

acetylcholine on M2

a. excitatory
b. inhibitory
c. both
d. neither

A

b. inhibitory

45
Q

norepinephrine on a1

a. excitatory
b. inhibitory
c. both
d. neither

A

a. excitatory

46
Q

opening of potassium channels

a. EPSP
b. IPSP
c. both
d. neither

47
Q

opening of sodium channels

a. EPSP
b. IPSP
c. both
d. neither

48
Q

closing chloride channels

a. EPSP
b. IPSP
c. both
d. neither

A

d. neither

49
Q

endorphin

a. amino acid
b. neuropeptides
c. monoamine
d. none of the given

A

d. none of the given

50
Q

dopamine

a. amino acid
b. neuropeptides
c. monoamine
d. none of the given

A

c. monoamine

51
Q

Orexin

a. amino acid
b. neuropeptides
c. monoamine
d. none of the given

A

b. neuropeptides

52
Q

Baclofen is a receptor agonist of which of the ff:

a. GABA
b. opioid peptides
c. glycine
d. endocannabinoids

53
Q

type of voltage-gated ion channel receptor of omega conotoxin

a. sodium channel
b. calcium channel
c. potassium channel
d. none of the choices

A

b. calcium channel

54
Q

neuronal system of adrenergic (NE) pathways

a. hierarchical
b. non-specific or diffuse
c. both
d. neither

A

b. non-specific or diffuse

55
Q

system major excitatory neurotransmitters are aspartate and glutamate

a. hierarchical
b. non-specific or diffuse
c. both
d. neither

A

a. hierarchical

56
Q

depends on secondary messengers to mediate intracellular signaling cascade

a. voltage-gated ion channels
b. ligand-gated ion channels
c. metabotropic receptors

A

c. metabotropic receptors

57
Q

Na channels that are highly concentrated on the axon hillock

a. voltage-gated ion channels
b. ligand-gated ion channels
c. metabotropic receptors

A

a. voltage-gated ion channels

58
Q

closing of potassium channels

a. EPSP
b. IPSP
c. both
d. neither

59
Q

glycine

a. amino acid
b. neuropeptides
c. monoamine
d. none of the given

A

a. amino acid

60
Q

muscimol is a receptor agonist of which of the ff:

a. GABA
b. opioid peptides
c. glycine
d. endocannabinoids

61
Q

which reduces the release of catecholamines from adrenergic synapses

a. amphetamine
b. tetanus toxin
c. capsaicin
d. reserpine

A

a. amphetamine

62
Q

type of ligand-gated receptor of Strychnine

a. nicotinic Ach receptors
b. GABA-A receptor
c. Glycine receptor
d. AMPA receptors

A

c. Glycine receptor

63
Q

Which has an AMPA receptor subtype?

a. acetylcholine
b. glutamate
c. dopamine
d. norepinephrine

A

b. glutamate

64
Q

this blocks “big Ca-activated” K channels

a. apamin
b. batrachotoxin
c. charybdotoxin
d. omega conotoxin

A

c. charybdotoxin

65
Q

neuronal system of dopaminergic pathways

a. hierarchical
b. non-specific or diffuse
c. both
d. neither

A

b. non-specific or diffuse

66
Q

system with interneurons utilizing inhibitory neurotransmitter glycine and GABA

a. hierarchical
b. non-specific or diffuse
c. both
d. neither

A

a. hierarchical

67
Q

multiple subunits to which neurotransmitters bind to open the channel

a. voltage-gated ion channel
b. ligand-gated ion channel
c. metabotropic receptors

A

b. ligand-gated ion channel

68
Q

does not result to direct gating of channels upon binding of neurotransmitter

a. voltage-gated ion channel
b. ligand-gated ion channel
c. metabotropic receptors

A

c. metabotropic receptors

69
Q

acetylcholine on M2

a. excitatory
b. inhibitory
c. both
d. neither

A

b. inhibitory

70
Q

serotonin on 5HT1A

a. excitatory
b. inhibitory
c. both
d. neither

A

b. inhibitory

71
Q

norepinephrine on B2

a. excitatory
b. inhibitory
c. both
d. neither

A

b. inhibitory

72
Q

HT2A

a. excitatory
b. inhibitory
c. both
d. neither

A

a. excitatory

73
Q

dopamine

a. excitatory
b. inhibitory
c. both
d. neither

A

b. inhibitory

74
Q

closing sodium channels

a. EPSP
b. IPSP
c. Both
d. Neither

A

d. Neither

75
Q

blocking of Ca

a. EPSP
b. IPSP
c. Both
d. Neither

76
Q

nitric oxide

a. amino acid
b. neuropeptides
c. monoamine
d. none of the given

A

d. none of the given

77
Q

glutamate

a. amino acid
b. neuropeptides
c. monoamine
d. none of the given

A

a. amino acid

78
Q

adenosine

a. amino acid
b. neuropeptides
c. monoamine
d. none of the given

A

a. amino acid

79
Q

Substance P

a. amino acid
b. neuropeptides
c. monoamine
d. none of the given

A

a. amino acid

aaa pp (8 decks)

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