3.3 - TRICHURIS TRICHIURA Flashcards

1
Q

other name

A

Triocephalus trichiura

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2
Q

common name

A

human whip worm

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3
Q

final host

A

man

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4
Q

habitat

A

large intestine

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5
Q

MOT

A

ingestion of eggs

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6
Q

infective stage

A

embryonated egg

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7
Q

diagnostic stage

A

egg

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8
Q
  • 30-45 mm
  • coiled posterior with single spicule and retractile sheath
A

male adult

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9
Q
  • 35-50mm
  • blunt posterior end
A

female adult

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10
Q

secretory cells

A

stichocytes

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11
Q

entire esophageal structure with stichocytes

A

stichosome

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12
Q

egg shape

A

football, barrel, lemon, Japanese lantern shape

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13
Q

unique diagnostic feature

A

bipolar refractile plugs at both ends of the egg

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14
Q
  • size: 50 to 54 um by 23 um
  • yellowish outer and transparent inner shell
A

general moprhology of eggs

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15
Q

unsegmented ovum

A

bile stained

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16
Q

inner shell

A

non-bile stained

17
Q

outer shell

A

bile stained

18
Q

life cycle

A
  1. mouth
  2. small intestine
  3. large intestine (adults)
  4. copulation
  5. stool
  6. soil
  7. embryonation
19
Q

Larvae are released and mature into adults in the colon, where they attach and survive up to ?

A

10 years

20
Q

Female adults: Lays ? eggs per day

A

3,000-7,000 eggs

21
Q

trichuris infection

A

Trichuriasis

22
Q

bleeding because it is attached to mucosa and would feed off the body

A

petechial hemorrhage

23
Q

intestinal bleeding (how much blood loss?)

A

0.005mL per day

24
Q

notable characteristic of trichuris infection

A

rectal prolapse

25
Q
  • rectum comes out of the perianal region that would harbor parasites
  • anus will be flipped inside out
A

rectal prolapse

26
Q

other clinical manifestations

A

reduced intellectual and cognitive development in children

27
Q

virulence factor

A

TT47 protein

28
Q
  • pore-forming protein
  • allows them to embed their whip-like structure or embed themselves to the intestinal walls of the patients
A

TT47 protein

29
Q

diagnosis

A
  • DFS
  • kato thick
  • kato katz
  • concentration test
30
Q

highly recommended diagnostic test

A

kato thick smear

31
Q

determines the intensity of the trichuris infection

A

kato katz

32
Q

extremely efficient in demonstration of eggs

A

zinc flotation method

33
Q

3rd most common roundworm of humans

A

Trichuris trichiura

34
Q

Children ? of age are the most commonly infected

A

5-15 years

35
Q

treatment

A

albendazole

36
Q

increases contact time between drug and parasites in diarrheic patients

A

Loperamide HCl