3.3 - TRICHURIS TRICHIURA Flashcards
other name
Triocephalus trichiura
common name
human whip worm
final host
man
habitat
large intestine
MOT
ingestion of eggs
infective stage
embryonated egg
diagnostic stage
egg
- 30-45 mm
- coiled posterior with single spicule and retractile sheath
male adult
- 35-50mm
- blunt posterior end
female adult
secretory cells
stichocytes
entire esophageal structure with stichocytes
stichosome
egg shape
football, barrel, lemon, Japanese lantern shape
unique diagnostic feature
bipolar refractile plugs at both ends of the egg
- size: 50 to 54 um by 23 um
- yellowish outer and transparent inner shell
general moprhology of eggs
unsegmented ovum
bile stained
inner shell
non-bile stained
outer shell
bile stained
life cycle
- mouth
- small intestine
- large intestine (adults)
- copulation
- stool
- soil
- embryonation
Larvae are released and mature into adults in the colon, where they attach and survive up to ?
10 years
Female adults: Lays ? eggs per day
3,000-7,000 eggs
trichuris infection
Trichuriasis
bleeding because it is attached to mucosa and would feed off the body
petechial hemorrhage
intestinal bleeding (how much blood loss?)
0.005mL per day
notable characteristic of trichuris infection
rectal prolapse
- rectum comes out of the perianal region that would harbor parasites
- anus will be flipped inside out
rectal prolapse
other clinical manifestations
reduced intellectual and cognitive development in children
virulence factor
TT47 protein
- pore-forming protein
- allows them to embed their whip-like structure or embed themselves to the intestinal walls of the patients
TT47 protein
diagnosis
- DFS
- kato thick
- kato katz
- concentration test
highly recommended diagnostic test
kato thick smear
determines the intensity of the trichuris infection
kato katz
extremely efficient in demonstration of eggs
zinc flotation method
3rd most common roundworm of humans
Trichuris trichiura
Children ? of age are the most commonly infected
5-15 years
treatment
albendazole
increases contact time between drug and parasites in diarrheic patients
Loperamide HCl
