3.3 Synapses, Drugs, and Addictions Flashcards
Agonist
A drug that mimics or increases the effect of a neurotransmitter
Antagonist
A drug that blocks a neurotransmitter
affinity (attraksjon)
compatibility. an attraction or force between particles that causes them to combine.
Eg. a drug has an affinity for a reseptor if it binds to it, like a key ino a lock.
Efficacy
a drug’s tendency to activate the receptor
Self-stimulation of the brain
Behaviour that is reinforced by electrical stimulation of a brain area
Stimulant drugs
Drugs that increase excitement, slertness, and activity while elevating mood and decreasing fatigue
Nucleus accumbens
Brain area that is rich in dopamine and is central to the brain’s reinforcement system
Cocaine
A drug that blocks reuptake of dopamine
Dopamine transporter
A protein that is reabsorbed at the presynaptic terminal
Methylphenidate (ritalin)
Stimulant drug prescribed for ADHD that increases the stimulation of dopamine synapses by blocking the reuptake of dopamine by the presynaptic neuron
Opiate drugs
Drugs derived from the opium poppy
Nicotine
A stimulant drug that stimulates certain acetylcholine receptors
Amphetamine
A drug that blocks reuptake of dopamine and other neurotransmitters
Type I (type A) alcoholism
Alcohol abuse with graual onset; only a weak genetic predisposition
Type II (type B) alcoholism
Alcohol abuse with rapid onset and a strong genetic basis
Withdrawl
Effects of drug cessation (slutt)
Tolerance
Decrease of effects
Cannabinoids
Any of the chemical compounds that are the active principles of marijuana
Halluciogenic drugs
Drugs that distort perception
Anandamide
Chemical that binds to cannabinoid receptors
9-tetrahydrocannabinol (9-THC)
Chemical contained in marijuana leaves
Methadone
Drug similar to heroin and morphine that is taken orally
2-AG (sn-2 arachidonylglycerol)
Chemical that binds to canabinoid receptors
Alcohol dependence (alcoholism)
The habitual use of alchohol despite medical or social harm
Antabuse (disulfram)
Drug that antagonizes the effects of acetaldehyde dehydrogenase by binding to its copper ion
A drug used in treatment of alcoholism, that acts by inducing nausea and other unpleasant symptoms following ingestion of alcohol