15.2 Schizophrenia Flashcards
Schizophrenia
A psychotic disorder characterized by a deteriorating ability to function in everyday life and by some combination of hallucinations, delusions, thought disorder, movement disorder, and inappropriate emotional expressions
Hallucinations
False sensory experiences
Positive symtoms
Presence of behaviors not seen in normal people
Delusions
Unjustifiable beliefs
Negative symptoms
Absence of behaviors ordinarily seen in normal people (e.g., lack of emotional expression)
DISC1 (disrupted in schizophrenia 1)
Gene that controls production of dendritic spines and the generation of new neurons in the hippocampus
Differential diagnosis
One that rules out other conditions with similar symptoms
Concordance
Similarity between individuals with regard to a trait
Season-of-birth effect
Tendency for people born in the winter to have a slightly greater probability of developing schizophrenia than people born at other times of the year
Neurodevelopmental hypothesis
Proposal that schizophrenia begins with abnormalities in the prenatal or neonatal development of the nervous system, based on either genetics or other influences
Antipsychotic (neuroleptic) drug
Drugs that tend to relieve schizophrenia and similar conditions
Chlorpromazine
(Thorazine) antipsycotic drug that relieves the positive symptomes of schizophrenia for most, though not all, patients
Butyrophenones
A chemical family that includes antipsychotic drugs (haloperidol) that relieve the positive symptomes of schizophrenia
Substance-induced psychotic disorder
Contition provoked by large, repeated doses of a drug
Phenothiazines
A chemical family that includes antipsychotic drugs (chlorpromazine) that relieve the positive symptoms of schizophrenia
