3.2 Polypeptide Synthesis processes Flashcards
What is Transcription
the process of turning genetic information stored in the DNA into an intermediary molecule mRNA
What is mRNA
an intermediary molecule, that is a messenger ribonucleic acid that is single stranded and genetically similar to DNA. it contains ribose sugar not deoxyribose and instead of thymine its uracil
First step of transcription
RNA polymerase binds to the promoter sequence upstream from a gene
Second step of transcription
As RNA polymerase moves along the DNA strand , a small region of DNA is unwound
Third step of transcription
RNA polymerase ‘reads’ the DNA template strand, matching complementary free floating nucleotides to create a chain containing the same coding information
Fourth step of transcription
A mRNA is sequentially synthesised by RNA polymerase, as it continues to move along the DNA strand
Fifth step of transcription
Terminator sequence and the transcription of DNA, and the newly formed mRNA molecule is released
What is Translation
The process of turning information encoded as mRNA into a polypeptide chain
Translation process
- mRNA docks to a ribosome
- the ribosome matches a complementary tRNA molecule to the mRNA by matching codon/anticodon sequences
- A polypeptide bond is formed between adjacent amino acid molecules which they carry
- the polypeptide chain is formed by continuous additions of amino acids
- when a stop sequence is reached, ribosome release mRNA and polypeptide molecule
- the polypeptide results in mature protein
What is a genotype
the genome or genetic makeup of an organism
What is a Phenotype
The outward appearance of an organism, including observable traits, biochemistry and physiology