3.19.14 35 EEG and epilepsy

Question 1

Excitatory NT?

Answer 1

Glutamate

Question 2

Inhibitory NT?

Answer 2

GABA

Question 3

What lobe is most commonly afflicted in epilepsy? What structure specifically?

Answer 3

Temporal lobe

Hippocampus

Question 4

What are the 5 cellular mechanisms of epilepsy?

Answer 4

1. Burst firing
2. Recurrent excitatory connections
3. Synaptic enhancement
4. Depression of inhibitory synapses
5. Non-synaptic spread

Question 5

What are the two main classifications of seizures?

Answer 5

Partial (focal) localization related

Primary generalized

Question 6

What characterizes simple partial seizures?

Answer 6

Maintenance of consciousness
Twitching (focal onset)
Aura

Question 7

What characterizes complex partial seizures?

Answer 7

Alteration of consciousness
Aura
Tuberous sclerosis

Question 8

What are the four types of primary generalized seizures?

Answer 8

Absence
Myoclonic
Atonic
Convulsive

Question 9

What characterizes Lennox Gastaut seizures?

Answer 9

Head drop + multiple seizure types
Mental retardation
Slow spike and wave
Early childhood

Question 10

What are the two types of benign focal epilepsy?

Answer 10

Benign rolandic (centro-temporal)
Benign occipital

Question 11

Post-ictal confusion is common in what types of seizures?

Answer 11

Complex partial seizure

Primary generalized convulsive seizure

Question 12

Do patients have auras for primary generalized convulsive seizures?

Answer 12

NO