3.10.14 Autonomics drug flashcards

1
Q

Amphetamine

A

Indirect-acting sympathomimetic

Induces release of stored catecholamines

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2
Q

Cocaine

A

Indirect acting sympathomimetic

Blocks reuptake at the NE and DA transporter

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3
Q

Muscarine toxicity

A
Toxicity = SLUDGE
Salivation
Lacrimation
Urination
Defecation
GI upset
Emesis
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4
Q

Neostigmine

A
Cholinesterase inhibitor
Postoperative/neurogenic ileus
Urinary retention
Myasthenia gravis (diagnostic)
Alzheimer's disease
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5
Q

Phenylephrine

A

Alpha agonist

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6
Q

Prazosin

A

Alpha blocker

Glaucoma

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7
Q

Propanolol

A

Beta blocker

Cardioselective blocker

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8
Q

Scopolamine

A

Anti-muscarinic

Anti-motion sickness (dry mouth!!!)

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9
Q

Tyramine

A

Indirect acting sympathomimetic

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10
Q

What drugs are nicotinic receptor agonists? used for?

A

Nicotine (smoking cessation)

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11
Q

What drugs are muscarinic receptor agonists? used for?

A

Muscarine and bethanechol (ileus and urinary retention; glaucoma)

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12
Q

What drugs block muscarinic receptors? used for?

A

Atropine and scopalamine (motion sickness; cholinergic toxicity; antidiarrheal; dilation of the eyes)

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13
Q

Toxicity of muscarinic antagonists?

A

Blind as a bat
Dry as a bone
Red as a beat
Mad as a hatter

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14
Q

What drugs are cholinesterase inhibitors? used for?

A

Neostigmine and organophosphates (Alzheimer disease; diagnosis of mysasthenia gravis; glaucoma

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15
Q

What shouldn’t you use if your pt has glaucoma?

A

Atropine (reduces outflow)

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16
Q

What drugs are alpha agonists?

A

Phenylephrine (A only)
Norepinephrine (A and B1)
Epinephrine

17
Q

What drugs are alpha antagonists?

A

Prazosin

18
Q

What drugs are beta agonists?

A

Albuterol
Epinephrine
Norepinephrine (A and B1)

19
Q

What drugs are beta antagonists?

A

Propanolol

20
Q

What drug should be used for asthma patients?

A

Albuterol (B agonist)

21
Q

What are drugs are indirect sympathomimetics?

A

Amphetamine
Tyramine
Cocaine