3.1 Flashcards
RA, SLE, hyperimmunity, HIV, sepsis, shock
what are some ways RA is diagnosed?
CBC: mod anemia and slight leukocytosis
ESR: elevated
Synovial Fluid Analysis: cloudy, milky, or dark yellow numerous leukocytes
Rheumatoid Factor Test: positive, titer of 1:160 or higher
RA diagnosing criteria
4 or more of the following: Morning stiffness for more than one hour for at least a month and a half
Arthritis and swelling of at least three joints for six weeks
Arthritis in the joints of the hand for a month and a half
Symmetric arthritis for a month and a half
Subcutaneous nodules
RF levels above the 95th percentile
Joint degeneration that is visible through X-rays
wat is a DMARD?
disease modifying antirheumatic drugs. These work by decreasing the underlying process that causes inflammatory arthritis
main goal of treating RA
reduce inflammation
What is SLE?
systemic lupus erythematosus. A chronic inflammation of connective tissues
clinical manifestations of lupus (SLE)
facial erythema (butterfly rash), arthritis, photosensitivity, pericarditis, fever, fatigue, mouth ulcers, erythematous rashes, neuro changes
SLE diagnosing criteria
4 or more of the following: butterfly rash, discoid rash, photosensitivity, mouth ulcers, arthritis, neuro disorders like seizures or psychosis, renal disorder, anemia, immunological disorder, antinuclear antibodies, cardiopulmonary involvement
what is fibromyalgia?
inflammatory disease that causes muscle pain and fatigue. sxs very similar to Lupus
what is the diagnosing criteria for fibromyalgia?
at least 11 out of 18 tender points AND generalized pain for 3+ months
opportunistic infections in AIDS
Destruction of CD4+ Cells–>immunosuppression
Protozoa/Fungus–>Pneumocystis carinii pneumonia
Fungi–>Candidiasis
Viruses–>Herpes simplex 1 and 2
Bacteria–>Tuberculosis
T-cell threshold for AIDS
CD4 T-cell level at 200 cells/mm3 or lower
