30/12/18

Question 1

What is cardiogenic shock?

Answer 1

Sudden inability of the heart to pump sufficient oxygen rich blood

Question 2

Describe the action of clonidine

Answer 2

Binds to a2 prejunctional receptor reducing the amount of NA released hence inhibiting the SNS

Question 3

In terms of metabolism what is phenylephrine more resistant to?

Answer 3

COMT but not MAO

Question 4

What is the caution with using isoprenaline?

Answer 4

Also stimulates b2 receptors = decrease venous return reflex tachycardia via the stimulation of baroreceptors.

Question 5

What is the plasma half life of dobutamine?

Answer 5

2 minutes

Question 6

Name a mixed andrenoceptor antagonist

Answer 6

carvedilol (a1+b1)

Question 7

What is hypertension defined as?

Answer 7

Consistently above 140/90 mmHg

Question 8

When treating hypertension what do betablockers do to sympathetic nerves?

Answer 8

They prevent the release of vasoconstrictors noradrenaline

Question 9

Name two beta 1 receptor antagonists?

Answer 9

Atenolol

Nebivolol - potentiates NO