3 Stroke Flashcards
Stroke statistics
- 5th leading cause of death in US
- leading cause of disability in adults
- 795,000 Americans each year, 75% first stroke, 25% recurrent
- in US, stroke every 40 seconds and someone dies every 4 minutes due to stroke
- 87% ischemic strokes, 13% hemorrhagic
ABCD2 prediction rule
- age >60 years = 1 point
- BP >140 or >90 = 1
- unilateral weakness with or without speech impairment = 2
- speech impairment without weakness = 1
- > 60 minutes = 2, 10-59 minutes = 1
- diabetes = 1
Higher score = higher 30 and 90 day stroke risk
CT for stroke
- primary imaging for initial evaluation
- rule out hemorrhagic stroke and may identify ischemic lesion, but may not see in early hours
- aids in decision whether to administer tPA
Computed Tomography Angiogram
- inject IV contrast followed by radiography
- clear images of cerebral blood vessels to see stenosis, occlusion, aneurysms, and vascular abnormalities
MRI
- detect edema in sub-acute phase that may not be visible on CT
- can’t use with pacemakers, some metallic implants
Magnetic Resonance Angiogram
-detect high grade atherosclerotic lesions and less common causes of ischemic stroke (carotid and vertebral artery dissection, venous thrombosis, etc.)
Positron emission tomography
- imaging of regional blood flow and cerebral metabolism
- determine areas of tissue where ischemia is reversible
Anticoagulation meds
- Heparin (Lovenox)
- Warfarin (Coumadin)
MCA stroke
- most common location
- primary motor and sensory cortices, Broca’s, Wernicke’s
- contralateral weakness (UE and face), sensory impairment
- aphasia if L
- neglect if R
Lacunar strokes
- deep branches of MCA (lenticulostriate arteries)
- high incidence in those with HTN and elderly
- supplies BG, internal capsule
- contralateral weakness
PCA stroke
- supplies occipital lobe, inferior part of temporal lobe, deep structures (diencephalon)
- contralateral homonymous hemianopsia
- contralateral sensory impairment, weakness
ACA stroke
- rare due to collateral circulation provided by anterior communicating artery
- supplies motor and sensory cortices (LE), SMA, prefrontal cortex
- contralateral weakness, sensory impairment (LE)
- frontal lobe behavioral abnormalities- poor judgment, decreased attention and motivation, difficulty regulating emotions
Watershed strokes
- affect areas of brain supplies by most distal branches of major cerebral arteries
- results from hypoperfusion (heart disease, cardiac arrest, shock, etc.)
- proximal arm and leg weakness with preservation of distal strength (“man in a barrel”
PICA stroke
- Lateral medullary syndrome or Wallenberg syndrome
- supplies cerebellum and medulla
- loss of pain and temperature on contralateral side of body and ipsilateral face
- dizziness/vertigo
- ataxia, diplopia, dysphagia, dysarthria
- Horner’s syndrome- caused by damage of sympathetic trunk to vertebral bodies. Ipsilateral miosis (pupil constriction), ptosis, decreased sweating
AICA stroke
- lateral pontine syndrome
- supplies cerebellum, CN VII and VIII
- ipsilateral ataxia
- contralateral weakness, sensory impairment (pain and temperature)
- dizziness/vertigo
Cranial nerve signs opposite long tract signs
Brainstem disorder
Loss of pain and temp, vibration, touch, position on different sides of body
SCI
Impairment of all sensory modalities on one side of body plus UMN signs
Cortical injury
Impairment of all sensory modalities on one side of body plus LMN signs
Peripheral nerve injury
Supratentorial
- damage to cerebral cortex or diencephalon
- cognitive, judgment, affect, and/or language deficits
Infratentorial
- damage to brainstem or cerebellum
- abnormal vitals, automatic movement adjustments, posture/gait, and/or breathing patterns
Thalamic pain syndrome
- initially presents as numbness that turns into debilitating burning
- may be accompanied by allodynia- pain from stimulus that would not normally be painful
Right optic nerve lesion
Blindness in R eye
Optic chiasm lesion
- loss of temporal fields in both eyes
- bitemporal hemianopsia
Lesion to uncrossed fibers from R eye
- loss of nasal field of R eye
- R nasal hemianopsia
Right optic tract lesion
- loss of L visual field
- L homonymous hemianopsia