3. Pain Medications Flashcards
Celebrex™
Pharmacologic Category + Drug Schedule
Celecoxib
- COX II-Inhibitor NSAID
- N/A Drug Schedule
Celebrex™
FDA Approved Indications/Uses
Celecoxib
- Osteoarthritis
- Rheumatoid arthritis
- Juvenile rheumatoid/idiopathic arthritis
- Dysmenorrhea
- Ankylosing spondylitis
- Prophylaxis of colorectal adenomas or polyps
Celebrex™
Adverse Effects
Celecoxib
- Diarrhea
- Headache
- Hypertension
- Abdominal pain
- Dyspepsia
- Peptic ulcer
- Stroke
- Nausea
- Infection
- Arthralgia
- Cough
- Fever
- Sinusitis
Celebrex™
Dosage Forms
Celecoxib
- Capsule
- 50mg
- 100mg
- 200mg
- 400mg
Celebrex™
Patient Education
Celecoxib
- Tell your doctor or health care professional if your pain does not get better. Talk to your doctor before taking another medicine for pain. Do not treat yourself.
- This medicine does not prevent heart attack or stroke. In fact, this medicine may increase the chance of a heart attack or stroke. The chance may increase with longer use of this medicine and in people who have heart disease. If you take aspirin to prevent heart attack or stroke, talk with your doctor or health care professional.
- Do not take medicines such as ibuprofen and naproxen with this medicine. Side effects such as stomach upset, nausea, or ulcers may be more likely to occur. Many medicines available without a prescription should not be taken with this medicine.
- This medicine can cause ulcers and bleeding in the stomach and intestines at any time during treatment. Ulcers and bleeding can happen without warning symptoms and can cause death.
Codeine/APAP 30/300mg
Pharmacologic Category + Drug Schedule
Tylenol with Codeine No.3™
- Opioid analgesic
- CIII
Codeine/APAP 30/300mg
FDA Approved Indications/Uses
Tylenol with Codeine No.3™
- Treatment of mild pain to moderate pain
Codeine/APAP 30/300mg
Adverse Effects
Tylenol with Codeine No.3™
- GI effects: Nausea, vomiting, constipation
- Headache
- Acute renal failure may occur in 25—30% of patients secondary to liver dysfunction
- Hematologic & oncologic: Agranulocytosis, thrombocytopenia
- Hypersensitivity reaction
- Respiratory: Dyspnea
- Dizziness, drowsiness, dysphoria, euphoria, sedation,
- Serotonin syndrome
- Flushing, faintness, palpitations, hypotension, orthostatic hypotension, and syncope
Codeine/APAP 30/300mg
Dosage Forms
Fenofibrate
- Tablet
- Elixir
- Oral solutions
Codeine/APAP 30/300mg
Patient Education
Tylenol with Codeine No.3™
- Administer with a full glass of water. May be taken with food or milk to minimize GI irritation.
- Avoid taking other drugs that have acetaminophen in them
- Avoid driving
- This drug may affect certain lab tests. Tell your health care providers and lab workers that you take this drug.
- •Long-term use of an opioid drug like this drug may lead to lower sex hormone levels. This may lead to signs like change in sex ability in men, no menstrual period in women, lowered interest in sex, or fertility problems.
- Taking an opioid drug like this drug may lead to a rare but very bad adrenal gland problem.
- Deadly breathing problems have happened with use of codeine in children.
Cyclobenzaprine
Pharmacologic Category + Drug Schedule
- Amrix™
- EnovaRX™
- Fexmid™
- Flexeril™
- Centrally-acting muscle relaxant
- N/A Drug Schedule
Cyclobenzaprine
FDA Approved Indications/Uses
- Amrix™
- EnovaRX™
- Fexmid™
- Flexeril™
- Muscle spasm
- Fibromyalgia
Cyclobenzaprine
Adverse Effects
- Amrix™
- EnovaRX™
- Fexmid™
- Flexeril™
- Dizziness
- Drowsiness
- Headache
- Xerostomia
- Acne vulgaris
- Dysgeusia
- Fatigue
- Nausea
- Palpitations
- Tremor
Cyclobenzaprine
Dosage Forms
- Amrix™
- EnovaRX™
- Fexmid™
- Flexeril™
- Tablet
- 5mg
- 7.5mg
- 10mg
- Capsule
- 15mg
- 30mg
- Topical powder
Cyclobenzaprine
Patient Education
- Amrix™
- EnovaRX™
- Fexmid™
- Flexeril™
- Tell your doctor or health care professional if your symptoms do not start to get better or if they get worse.
- You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
- If you are taking another medicine that also causes drowsiness, you may have more side effects. Give your health care provider a list of all medicines you use. Your doctor will tell you how much medicine to take. Do not take more medicine than directed. Call emergency for help if you have problems breathing or unusual sleepiness.
- Your mouth may get dry. Chewing sugarless gum or sucking hard candy and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.
Fentanyl
Pharmacologic Category + Drug Schedule
- CII
- CNS-synthetic opiate agonist
- Opiate anesthetics
- CII
Fentanyl
FDA Approved Indications/Uses
- ABSTRAL™
- Actiq™
- Duragesic™
- Fentora™
- IONSYS™
- Lazanda™
- Onsolis™
- Sublimaze™
- SUBSYS™
- #### Control of moderate to severe pain
- #### Management of chronic severe pain in opioid-tolerant patients who require daily, around-the-clock, long-term opioid treatment
- Analgesia and/or sedation
Fentanyl
Adverse Effects
- ABSTRAL™
- Actiq™
- Duragesic™
- Fentora™
- IONSYS™
- Lazanda™
- Onsolis™
- Sublimaze™
- SUBSYS™
- CNS: Confusion, dizziness, drowsiness, fatigue, headache, sedated state
- respiratory depression, respiratory arrest, and apnea
- Dehydration
- Hyperamylasemia
- GI: Constipation, nausea, vomiting
- Cardiovascular: Atrial fibrillation, bigeminy, cardiac arrhythmia, chest pain, deep vein thrombosis, edema, hypertension, hypotension, myocardial infarction, orthostatic hypotension, palpitations, peripheral edema, pulmonary embolism
Fentanyl
Dosage Forms
- ABSTRAL™
- Actiq™
- Duragesic™
- Fentora™
- IONSYS™
- Lazanda™
- Onsolis™
- Sublimaze™
- SUBSYS™
- Buccal tablet
- Dissolving film
- Oral lozenge
- Injection
- Nasal spray
- Sublingual tablet/spray
- Transdermal patch
Fentanyl
Patient Education
- ABSTRAL™
- Actiq™
- Duragesic™
- Fentora™
- IONSYS™
- Lazanda™
- Onsolis™
- Sublimaze™
- SUBSYS™
- Avoid driving and doing other tasks or actions that call for you to be alert.
- To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs.
- Long-term or regular use of opioid drugs like this drug may lead to dependence. Lowering the dose or stopping this drug all of a sudden may cause a greater risk of withdrawal or other severe problems. Tell your doctor if you have more pain, mood changes, thoughts of suicide, or any other bad effects.
- Do not take more than what your doctor told you to take. Taking more than you are told may raise your chance of very bad side effects.
- Do not take this drug with other strong pain drugs.
- If you drink grapefruit juice or eat grapefruit often, talk with your doctor.
- This drug may raise the chance of seizures in some people, including people who have had seizures in the past.
- Long-term use of an opioid drug like this drug may lead to lower sex hormone levels. This may lead to signs like change in sex ability in men, no menstrual period in women, lowered interest in sex, or fertility problems.
- If you are 65 or older, use this drug with care. You could have more side effects.
- This drug may cause harm to the unborn baby if you take it while you are pregnant. If you are pregnant or you get pregnant while taking this drug, call your doctor right away.