3: Inflammation I Flashcards
What happens to blood vessels in the event of injury?
Vasodilation
Which chemicals mediate vasodilation in response to injury?
Histamine
Nitric oxide
What happens the rate of blood flow after vasodilation?
Slows down
When blood vessels dilate, large white blood cells can move along the periphery of the lumen. What is this called?
White cell margination
During inflammation, ___ on the lumenal walls bind to marginated white cells.
proteins
Which cytokines increase the expression of adhesion molecules on the walls of blood vessels?
Histamine
Thrombin
TNF
IL-1
In inflammation, blood vessels become ___ and water follows protein into tissues.
leaky
What process involves cells following a chemical gradient?
Chemotaxis
What is rubor?
Redness due to vasodilation and increased perfusion
What is calor?
Heat
Increased perfusion, increased vascular permeability
What is tumor?
Swelling
What is dolor?
Pain
Which inflammatory cell characterises acute inflammation?
Neutrophil
Why are neutrophils also known as polymorphs?
Multi-segmented nucleus
Neutrophils contain ___.
granules
