3- complications of pneumonia Flashcards

1
Q

what is pneumonia?

A

form of acute respiratory infection that affect the lungs where alveoli filled with pus

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2
Q

what do bronchial breath sounds suggest?

A

implies airways full of pus and pus transmitting sound from large bronchial airways to your stethoscope

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3
Q

what is empyema?

A

pus in pleural space = complication of pneumonia
- needs intercostal drain

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4
Q

are primary empyema iatrogenic or idiopathic?

A

can be both = often iatrogenic (doctors fault), many idiopathic (spontaneous)

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5
Q

what signs mean just a simple parapneumonic effusion?

A
  • Clear fluid
  • pH > 7.2 (pretty benign)
  • LDH < 1000
  • Glucose > 2.2 (low glucose benign as no cells eating up sugar)
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6
Q

what signs mean a complicated parapneumonic effusion?

A
  • pH < 7.2
  • LDH > 1000
  • Glucose < 2.2
  • Requires Chest Tube Drainage
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7
Q

what signs mean empyema?

A
  • Frank pus
  • No other tests required
  • Requires Chest Tube Drainage
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8
Q

what is the most common organisms causing empyema?

A

aerobic organisms: both gram positive + gram negative

gram positive: strep pneumoniae, staph aureus, strep milleri (found in healthy people’s mouth, flu like illness encourage bacteria to travel down and cause infection for some reason)

gram negative: e.coli, pseudomonas, klebsiellae

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9
Q

are empeyemas ever caused by anaerobes?

A

in 13% cases = not common = usually in severe pneumonia or poor dental hygiene

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10
Q

what are you looking for in chest x-ray?

A

persisting or new effusion

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11
Q

what is the preferred investigation for checking complications of pneumonia?

A

ultrasound as simple bedside test with targeted sampling

= the appearances will give clue to complexity of fluid

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12
Q

what is purpose of CT scan in pneumonia complication?

A
  • Differentiation between Empyema and Abscess
  • Allows extent of effusion/empyema to be appreciated
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13
Q

what are you looking for on chest x-ray?

A
  • look for meniscus (characteristic appearance of the fluid level within the pleural space, resembling a meniscus shape indicating pleural effusion)
  • D -sign or split pleural sign (concave shape that looks like a D indicating empyema)

= some are obvious, some are not - not always large

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14
Q

what is antibiotics for empyema treatment?

A

IV antibiotics = amoxicillin + metronidazole or co-amoxiclav = a broad spectrum as often polymicrobial and need anaerobic cover

Oral antibiotic = usually co-amoxiclav for 5 weeks, directed towards cultured bacteria

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15
Q

what other treatment can be given for empyema?

A

intrapleural fibrinolytics = attempt to break down inflammation to try and help patient get better more quickly

  • if complicated effusion and dont get better with drain & antibiotic = give 2 drugs (tPA and DNA) in co,bimatoon up the drain and suddenly all the fluid comes out
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16
Q

what is an intrapulmonary abscesses?

A
  • A circumscribed necrotic infection within the lung parenchyma
  • Can sometimes be hard to distinguish from an empyema!
17
Q

what is helpful in diagnosing intrapulmonary abscess?

A

CT important for helping

18
Q

what are the symptoms like for intrapulmonary abscesses?

A

similar to lung cancer symptoms:
- Indolent presentation (little pain)
- Weight loss common
- Lethargy, tiredness, weakness
- Cough ± sputum, often suddenly worse
- High mortality if not treated

19
Q

what are common preceding illnesses of intrapulmonary abscesses?

A
  • Pneumonic infection
  • Post viral
  • Foreign body
20
Q

what are the different angle on CT suggest?

A

acute angle = abscess
obtuse angle = empyema

21
Q

what should you NOT drain?

A

an abscess

22
Q

what are pathogens that cause abscess?

A
  • bacteria (strep, staph, e.coli, gram negative)
  • funghi (aspergillus)
  • septic emboli (right sided endocarditis, infected DVT, septicaemia)
23
Q

why are intravenous drug users more vulnerable to abscess?

A
  • Inject into groin
  • DVT
  • Infection
  • PE + Abscesses
24
Q

what is treatment of abscess?

A
  • Prolonged courses of antibiotics – sometimes for months!
  • Occasionally surgery, but drainage is much less common than for empyema, and carries risk
25
Q

what makes aspiration pneumonia more likely?

A
  • Vomiting increases risk
  • Lowered conscious level means higher risk of aspirating foreign material
  • Pharyngeal pouch are outpouchings of mucosa and submucosa in posterior pharyngeal wall which can trap food particles & secretions
  • Hypogammaglobulinemia (deficiency of immunoglobulins in blood which means increased risk of aspiration pneumonia, respiratory infections)
26
Q

what are some key images of complications of pneumonia?

A

ultrasound and CT