3-2 BIO-1010 Study Guide Flashcards

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1
Q

What are two basic differences between innate immunity and adaptive immunity?

A

Innate immunity is the body’s first line of defense and is non-specific; adaptive immunity is specific to particular pathogens and has a memory component.

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2
Q

List two external physical barriers that are part of the innate immune system.

A

Skin and mucous membranes.

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3
Q

What is an antigen?

A

An antigen is a substance that triggers an immune response, typically by being recognized as foreign by the immune system.

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4
Q

How are macrophages and natural killer cells involved in innate immunity?

A

Macrophages engulf and digest pathogens; natural killer cells destroy infected or cancerous cells.

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5
Q

How is histamine involved in the inflammatory response?

A

Histamine increases blood flow and the permeability of capillaries, allowing immune cells to access affected tissue.

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6
Q

What are the four signs of inflammation?

A

Redness, heat, swelling, and pain.

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7
Q

What does it mean when we say that adaptive immunity has a memory?

A

Adaptive immunity has a memory, meaning it can recognize and respond more quickly to pathogens it has encountered before.

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8
Q

How are humoral immunity and cell-mediated immunity different, in terms of their targets?

A

Humoral immunity targets pathogens in bodily fluids using antibodies; cell-mediated immunity targets infected cells directly.

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9
Q

What are the two types of B lymphocytes that are involved in humoral immunity?

A

Plasma cells and memory B cells.

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10
Q

What are antibodies, and what type of cell produces them?

A

Antibodies are proteins that bind to specific antigens to neutralize them, produced by B lymphocytes.

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11
Q

What are the four types of T lymphocytes that are involved in cell-mediated immunity?

A

Helper T cells, cytotoxic (killer) T cells, regulatory T cells, and memory T cells.

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12
Q

List the functions of those four types of T lymphocytes.

A

Helper T cells activate other immune cells, cytotoxic T cells destroy infected cells, regulatory T cells modulate the immune response, and memory T cells provide long-term immunity.

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13
Q

How does the human immunodeficiency virus (HIV) cause immunodeficiency?

A

HIV targets and destroys helper T cells, weakening the immune response and leading to immunodeficiency.

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14
Q

How do vaccinations work?

A

Vaccinations expose the immune system to a harmless form of an antigen, prompting it to develop memory cells for future protection.

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15
Q

How are the surfaces of the red blood cells different in these four blood types: A, B, AB, and O?

A

Type A has A antigens, type B has B antigens, AB has both A and B antigens, and type O has no antigens on the surface.

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16
Q

Why does someone with type O blood have trouble receiving a transfusion of any other type of blood?

A

Type O blood lacks A and B antigens, so it will react against them if introduced through a transfusion.

17
Q

What goes wrong in autoimmune diseases?

A

In autoimmune diseases, the immune system mistakenly attacks the body’s own tissues.

18
Q

What goes wrong in allergies?

A

In allergies, the immune system overreacts to harmless substances, causing inflammation and other symptoms.