2a plasma membrane Flashcards

1
Q

epithelia

A

sheets of tissue that cover all body surfaces

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2
Q

amphipathic

A

molecule with both polar and nonpolar regions

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3
Q

ex of amphipathic

A

phosphatidylcholines are common in animal cell membranes)

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4
Q

when the melting point is low, is it going to be more or less fluidity?

A

more

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5
Q

Would you expect a thermo-conforming animal to have

A

more unsaturated bonds (as a phosphatdyethanolamines) which is more than phophatidylcholines

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6
Q

integral

A

permanently embedded in the membrane

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7
Q

peripheral

A

connected to the membrane, but removable

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8
Q

aqueous pores

A

channels through which aqueous solutions
can pass from one side of the membrane to the other.

type of channel protein

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9
Q

Channel proteins

A

Control

diffusion of aqueous solutes
osmosis of water

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10
Q

Transporter (carrier) proteins

A

Move specific molecules across a membrane by reversibly (non-covalently) bonding with them to facilitate transport

-can be active or facilitative

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11
Q

Membrane-bound Enzymes

A

Protein catalysts of various types embedded in membranes

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12
Q

Receptor proteins

A

– exact def of carrier proteins but can cause signal transduction

– signal transduction: 1. primary messenger, which may be a chemical signal, electrical pulse, or even physical stimulation. Then, the receptor protein embedded in the cellular membrane must accept the signal. Upon receiving the signal, this protein goes through a conformational change. This changes its shape and thus, how it interacts with the molecules around it.

  1. Some proteins activate other molecules, called second messengers, which carry the message to the nucleus or other organelles. Other proteins use the energy from ATP to activate enzymes, which carry out metabolic reactions.

–responsible for mediating responses to chemical signals arriving at the cell membrane.

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13
Q

Structural proteins

A
  • anchor intracellular elements to the cell membrane
  • form cell junctions
  • form the protein infrastructure of the membrane
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14
Q

epithelium

A
  • –lines a cavity in an organ or body
  • –forms boundaries between body regions
  • –forms boundaries between an animal and its external environment
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15
Q

apical (mucosal) surface

A

facing the side of an open membrane

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16
Q

basal (serosal) region

A

towards the tissue to which the epithelium is attached

17
Q

basement membrane or basal lamina

A
  • — thin, permeable, non-living, non-cellular fibrous matrix
  • — allow gas exchange
18
Q

name 3 of the simple and stratified epithelia

A
  1. squamous epithelium (cell width > height)
  2. cuboidal epithelium (cell width = height)
  3. columnar epithelium (cell width < height)
19
Q

simple vs stratified

A

stratified has more than one layer

20
Q

pseudo stratified

A

really one layer but looks like more than one layer because nuclei are on opp sides

21
Q

What is the functional significance of microvilli? (How do they increase transport efficiency?)

A

increase surface area for transport across membranes

22
Q

brush border

A

microvilli often resemble the bristles of a brush when viewed under the microscope, a row of microvilli

23
Q

tight junctions

A

Found only in vertebrates.
Block the interstice between two adjacent cells
Prevent interstitial movement of solutes from apical to basal regions. ( sealed together)
Substances must enter via cell membrane channels.
serve as barriers and prevent leaks

24
Q

Septate junction

A

used as tight junctions for invetebrates

25
Q

isoenzymes

A

as multiple forms of enzymes) are enzymes that differ in amino acid sequence but catalyze the same chemical reaction. These enzymes usually display different kinetic parameters (e.g. different KM values), or different regulatory properties.

26
Q

covalent modulation

A

activation or inactivation of enzymes, either by phosphorylation/dephosphorylation or by proteolytic cleavage. A major means of regulation of enzyme action by hormones.