2A - Neurohistology (1) Flashcards
Neurocytology
-cells associated with nervous system
Neurohistology
-cells associated to form tissues
CNS cell types:
- Neurons: main functional elements
- Glia: supporting cells
- Ependymal cells: Nervous system develops from neural tube, which is hollow. CNS maintains that hollowness with various spaces inside. Spaces are lined with specacialized tissue called ependyma
- Blood vessels
Coming off of cell body
dendrites
Axons are ensheathed by glial cells
Produce white fatty myelin
Myelin in not continuous
Nodes of Raniver interrupt
Nissl Stain
- can see cell bodies
- CANNOT see dendrites/axons/neurites
- cytoplasm of glial cells does not stain well
Nucleolus
- site at which ribosomal RNA is synthesized
- heavy protein synthesis
Axon hillock
- lacks Nissl
- Action potentials generated
- 1 spike trigger zone
Franz Nissl
- Lumbar puncture - drain CSF that fills inside CNS
- Staining
Neuronal Classifications
1) . size of cell body
2) . shape of cell body/dendrites
3) . presence or absence of spines
4) . axonal morphology
5) . chemical identity
Cell body shapes
1) Round
2) Spindle shaped (fusiform) –> slender, elongated, ellipsoidal-shape
3) Multipolar (many dendrites)
4) Pyramidal
Space between neurons
Neuropil
Cortical pyramidal cells
- 1 big dendrite go in same dierction
- dendrites point toward surface of brain
Nissl Stain
-can see space