2a Mock 1 Flashcards

1
Q

`What CVS stuff must you give patients with an MI?

A

Dual anti platelet therapy - aspirin and a PY12 inhibitor e.g. clopidogrel

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2
Q

What is the pharmacology of spironolactone?

A

Inhibition of the aldosterone receptor in the distal tubules

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3
Q

What are the causes of hypercalcaemia?

A

CHIMPANZEES
Calcium supplements, Hydrochlorothiazide, Iatrogenic/Immobilisation, Multiple myeloma/Medication (lithium), Parathyroid hyperplasia, Alcohol, Neoplasm, Zollinger ellison syndrome, Excessive Vit D, Excess Vit A, Sarcoidosis

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4
Q

What is carcinoid syndrome?

A

A paraneoplastic syndrome that has a classical triad of:
Cardiac involvement
Diarrhoea
Flushing

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5
Q

What is the cause of carcinoid syndrome?

A

Paraneoplastic tumour cells producing 5-HT

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6
Q

What is 1st line in treating h.pylori?

A

PPI + Amoxicillin + clarithromycin/metronidazole

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7
Q

Where do PPIs act on?

A

Parietal cells

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8
Q

What is the most common type of renal stone?

A

Calcium oxalate

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9
Q

Give 5 common causes of UTI

A
KEEPS
Klebsiella
E. Coli – most common
Enterococcus
Proteus/pseudomonas
Staphylococcus saprophyticus
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10
Q

What is furosemide?

A

Loop diuretic

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11
Q

What is the action of loop diuretics?

A

Act on ascending limb of loop of Henle

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12
Q

What can iron deficiency anaemia do to reflexes?

A

Hyporeflexia

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13
Q

What is the pharmacokinetics?

A

The action of the body on the drug

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14
Q

What is pharmacodynamics?

A

The action of the drug on the body

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15
Q

Which heart valve is most commonly affected in infective endocarditis?

A

Tricuspid

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16
Q

What is the 1st line treatment for osteoporosis?

A

Alendronic acid and AdCal

17
Q

What is the mechanism of action for bisphosphonates?

A

Inhibit bone resorption through the inhibition of enzyme (Farnesyl Pyrophosphate synthase) which reduces osteoclast activity

18
Q

What is the 1st line management of ankylosing spondylitis?

A

Physiotherapy and NSAIDs

19
Q

What drug is used to control jerky movements seen in huntingtons?

A

Risperidone