2a Mock 1 Flashcards
`What CVS stuff must you give patients with an MI?
Dual anti platelet therapy - aspirin and a PY12 inhibitor e.g. clopidogrel
What is the pharmacology of spironolactone?
Inhibition of the aldosterone receptor in the distal tubules
What are the causes of hypercalcaemia?
CHIMPANZEES
Calcium supplements, Hydrochlorothiazide, Iatrogenic/Immobilisation, Multiple myeloma/Medication (lithium), Parathyroid hyperplasia, Alcohol, Neoplasm, Zollinger ellison syndrome, Excessive Vit D, Excess Vit A, Sarcoidosis
What is carcinoid syndrome?
A paraneoplastic syndrome that has a classical triad of:
Cardiac involvement
Diarrhoea
Flushing
What is the cause of carcinoid syndrome?
Paraneoplastic tumour cells producing 5-HT
What is 1st line in treating h.pylori?
PPI + Amoxicillin + clarithromycin/metronidazole
Where do PPIs act on?
Parietal cells
What is the most common type of renal stone?
Calcium oxalate
Give 5 common causes of UTI
KEEPS Klebsiella E. Coli – most common Enterococcus Proteus/pseudomonas Staphylococcus saprophyticus
What is furosemide?
Loop diuretic
What is the action of loop diuretics?
Act on ascending limb of loop of Henle
What can iron deficiency anaemia do to reflexes?
Hyporeflexia
What is the pharmacokinetics?
The action of the body on the drug
What is pharmacodynamics?
The action of the drug on the body
Which heart valve is most commonly affected in infective endocarditis?
Tricuspid