2.7 nsci in the 2000s Flashcards
1
Q
main scientists?
A
o’keefe, mosers, tonegawa, joesselyn
2
Q
main ideas?
A
developments in modern genetic methods to manipulate memory and other brain functions
3
Q
john o’keefe + the mosers?
A
spatial mapping
- discovered cells in hippocampus that control the brain’s positioning system
place cells: fire when in at certain place
grid cells: create precise coordinate system
4
Q
susumu tonegawa?
A
pioneered transgenic and gene-KO technologies
used optogenetics to identify and manipulate memory engram neurons
5
Q
sheena josselyn?
A
uses optogenetics
discovered that memories can be implanted and erased in mice
