2.7 MEMBRANE LIPIDS: PHOSPHOLIPIDS Flashcards

1
Q

● three common types of membrane lipids

A

● (phospholipids, sphingoglycolipids, and cholesterol)

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2
Q

● Most contain an even number of carbon atoms. Carbon chain length is up to 24 carbon atoms

A

Fatty acids)

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3
Q

● Classification Based on Degree of Unsaturation

A

● SATURATED, MONOUNSATURATED AND POLYUNSATURATED)

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4
Q

● No double bonds are present in the carbon chain. Dietary effect is an increase in heart disease risk

A

(Saturated)

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5
Q

● Classification Based on Configuration of Double Bond for monounsaturated and polyunsaturated fatty acids

A

( CIS AND TRANS

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5
Q

● One double bond is present in the carbon chain. Dietary effect is a decrease in heart disease risk

A

monounsaturated

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5
Q

● Two or more double bonds are present in the carbon chain. Dietary effect is “mixed”; there have been several conflicting studies relative to heart disease risk.

A

polyunsaturated

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5
Q

● fatty acids have effects on blood chemistry similar to those of saturated fatty acids

A

(TRANS)

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5
Q

● First double bond is six carbons away from the CH3 end of the carbon chain. Linoleic acid

A

● (18:2) is the primary member of this family. (omega-6)

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5
Q

___ is a lipid that contains one or more fatty acids, a phosphate group, a platform molecule to which the fatty acid(s) and the phosphate group are attached, and an alcohol that is attached to the phosphate group

A

phospholipid

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6
Q

● Classification Based on Location of Double Bond for polyunsaturated fatty acids

A

omega-3 and omega-6)

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7
Q

● First double bond is three carbons away from the CH3 end of the carbon chain. Linolenic acid (18:3) is the primary member of this family.

A

. (omega-3

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8
Q

● The platform molecule on which a phospholipid is built may be the________ OR __________________

A

( 3-carbon alcohol glycerol or a more complex C18 aminodialcohol called sphingosine)

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9
Q

_____ is a lipid that contains two fatty acids and a phosphate group esterified to a glycerol molecule and an alcohol esterified to the phosphate group
contains ester linkages
undergo hydrolysis and saponification reactions that contains five reaction products

A

(Glycerophospholipid)

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10
Q

____ is the parent source for the minus one charged phosphate group used in the formation of glycerophospholipids

A

(phosphoric acid)

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11
Q

● 3 amino alcohol groups attached to the phosphate group in glycerophospholipid

A

● (choline, ethanolamine, or serine)

12
Q

● Glycerophospholipids containing these three amino (choline, ethanolamine, or serine) alcohols are respectively known as?

A

● (phosphatidylcholines, phosphatidylethanolamines, and phosphatidylserines)

13
Q

● Glycerophospholipids function almost exclusively as components of?

A

cell membranes

14
Q

● hydrophobic (“water-hating”) portion of glycerophospholipid

A

● (the non polar fatty acid groups — tails)

15
Q

● hydrophilic(“water-loving”) portion of glycerophospholipid______

A

(The polar head group– choline and phosphate)

16
Q

● also known as lecithins, are waxy solids that form colloidal suspensions in water. Egg yolks and soybeans are good dietary sources of these lipids,The enzyme lecithinase in the intestine hydrolyzes before it passes to body fluids. It is made in the liver. The food industry used them as emulsifiers to promote the mixing of otherwise immiscible materials. Mayonnaise, ice cream, and custards are some of the products they are found in

A

phosphatidylcholines

17
Q

_________also known as cephalins. These compounds are found in heart and liver tissue and in high concentrations in the brain. They are important in blood clotting

A

Phosphatidylethanolamines and phosphatidylserines

18
Q

● is a lipid that contains one fatty acid and one phosphate group attached to a sphingosine molecule and an alcohol attached to the phosphate group

A

(sphingophospholipid)

18
Q

● All phospholipids derived from sphingosine have______

A

● ((1) the fatty acid attached to the sphingosine —NH2 group via an amide linkage (2) the phosphate group attached to the sphingosine terminal —OH group via an ester linkage and (3) an additional alcohol esterified to the phosphate group.)

19
Q

● tails of the Sphingophospholipids

A

● ( the fatty acid and the long carbon chain of sphingosine)

20
Q

● The polar head of Sphingophospholipids

A

● ( PHOSPHATE GROUP WITH ESTERIFIED ALCOHOL)

21
Q

● Sphingophospholipids in which the alcohol esterified to the phosphate group is choline are called ___________ and are found in all cell membranes and are important structural components of the myelin sheath, the protective and insulating coating that surrounds nerves

A

sphingomyelins

21
Q

● Two types of phospholipids are?

A

● glycerophospholipids and sphingophospholipids

21
Q
  1. Based on the biological function, phospholipids are classified as?
A
  • membrane lipids
22
Q
  1. Which of the following types of lipids contain both ester and amide linkages?
A
  • sphingoglycolipids
23
Q
  1. Which of the following statements about the molecule sphingosine is correct?
A
  • 2 hydroxyl group and one amino group
24
Q
  1. when the “head and 2 tails” structural model is applied to glycerophospholipid, the 2 tails are?
A
  • both fatty and acid residue
25
Q
  1. When the “head and 2 tails” structural model is applied to sphingophospholipid, the 2 tails are?
A
  • The fatty residue and part of the sphingosine molecule
26
Q
  1. In terms of head and two tails model for phospholipid
A
  • both tails are hydrophobic