26 WJEC Biology AS Level - Marianne Izen - 2nd Edition Flashcards
Describe the secondary structure of protein
This is the shape that the polypeptide chain forms as a result of hydrogen bonding between the -O on -CO groups and the -H on-NH groups in the peptide bonds along the chain.
This causes the long polypeptide chain to be twisted into a 3D shape.
The spiral shape is the a-helix.
Another, less common, arrangement is the ẞ-pleated sheet.
The protein keratin has a high proportion of a-helix and the protein fibroin, in silk, has a high proportion of ẞ-pleated sheet.
A - a- 1,4- glycosidic
B - ester
C - peptide
A - tertiary
B - secondary
C - primary
D - quarternary
Describe the primary structure of proteins
This is the order of the amino acids in a polypeptide chain.
Polypeptides have up to 20 different types of amino acid.
They can be joined in any number, order and combination, so there is a huge number of possible polypeptides.
The primary structure is determined by the base sequence on one strand of the DNA molecule.