2.6 cell division and diversity Flashcards
state what the cell cycle is and outline its stages
It is a regulated cycle of division with intermediate growth periods
Interphase
mitosis/meiosis
cytokenesis
outline what happens during interphase
G0 - cells may undergo apoptosis (programmed cell death), It is a resting phase triggered during early G1
G1 - cell synthesises proteins for replication and cell size doubles
S - DNA replicates = chromosomes consist of 2 sister chromatids joined at a centromere
G2 - organelles divide
what is the purpose of mitosis
produces 2 genetically identical cells for
growth
repair
asexual reproduction
name the stage of mitosis
Prophase
Metaphase
Anaphase
Telophase
outline what happens during prophase
chromosomes condense, becoming visible
centrioles move to opposite poles of cell and mitotic spindles form
Nuclear envelope and nucleolus break down so chromosomes are free in the cytoplasm
outline what happens during metaphase
sister chromatids line up at the cell equator, attaches to the mitotic spindles by the centromeres
outline what happens during anaphase
spindle fibres contract and centromeres divide
sister chromatids sperate into 2 distinct chromosomes and are puled to opposite poles of the cell
spindle fibres break down
outline what happens during telophase
chromosomes decondense becoming non-visible again
new nuclear envelopes form around each set of chromosomes each are genetically identical
how is the cell cycle regulated?
Checkpoints regulated by cell signalling proteins ensure that damaged cells don’t progress to the next stage.
What is meiosis?
Type of nuclear division that results in the formation of cells containing half the number of chromosomes found in the parent cell.
What is the significance of meiosis in the life cycle?
During sexual reproduction the gamete cells only need half the normal amount of chromosomes (haploid cells)
Define homologous pairs.
A homologous pair of chromosomes has the same genes and all of the same alleles of that gene will appear at similar locations (locus) on that chromosome.
Although they may have the same genes their alleles can be different.
How many chromosomes and chromatids are there in the cell before and after meiosis?
Chromosomes:
before 46
after interphase 46
after meiosis 1 23
after meiosis 2 23
Chromatids:
before 46
after interphase 92
after meiosis 1 46
after meiosis 2 23
Define bivalent and chiasma.
pair of homologous chromosomes
chiasma - point of contact between bivalents
What are the 4 differences between meiosis and mitosis?
1- Meiosis produces genetically different haploids
2- meiosis has 2 divisions whereas mitosis has only 1
3- meiosis produces 4 haploids for sexual reproduction with 23 chromosomes. Whereas, mitosis produces 2 genetically identical cells with 46 chromosomes for asexual reproduction and growth and repairs
4- No bivalent in mitosis so chiasma don’t form.
Outline what happens in prophase 1.
The nuclear envelope breaks down and chromosomes condense, which then come together in their homologous pairs.
Crossing over occurs here where non-sister chromatids wrap around each other and may swap sections so that alleles are shuffled.
Outline what happens in metaphase 1.
The homologous pairs align at the equator at the cell and each attaches to a spindle thread by its centromere.
Outline what happens in anaphase 1.
The members of each pairs are pulled apart by motor proteins that drag them along the spindle threads.
The centromeres do not divide and each chromosome consists of two chromatids.