#25 Jasani - Basics of Sleep

Question 1

You are reading the sleep waveforms and you interpret a K-complex and a sleep spindle. What stage was your patient in?

Answer 1

Stage 2
K complex - sharp
Sleep spindle - high frequency

Question 2

Your child awakens you from sleep. You remember having a great dream about being at the beach. What type of sleep were you awaken from?

Answer 2

REM (REMember)

Question 3

Eye movement is seen on the EOG. What type of sleep are you in?

Answer 3

REM

Question 4

A patient is beginning an in lab sleep study. There are no EEG changes on the monitor. Is the patient asleep?

Answer 4

No. There must be EEG changes.

Question 5

Your patient is a type II diabetic and comes in complaining of memory lapses and aches in her muscle. She comments that her husband says she is irritable. She can’t help it with the workload she is dealing with. She says she works until 11 at night. What might be your ddx?

Answer 5

sleep deprivation

Question 6

RT works evenings and some rotating shifts during the night. What might be happening to his circadian rhythm?

Answer 6

Circadian rhythm is being disrupted.

Jet lag can also disrupt sleep.

Question 7

In the generation of sleep, what neurotransmitter does caffeine inhibit?

Answer 7

Adenosine

Question 8

You are on an acetylcholine receptor antagonist. What type of sleep will be affected?

Answer 8

REM

Question 9

Your patient has a hypocretin (orexin) system dysfunction. What sleep disorder may result?

Answer 9

Narcolepsy

Cataplexy

Question 10

What pro-inflammatory mediators promote sleep?

Answer 10

Interleukin-1
IL-1B
TNF - Alpha
PG
CRP
GHRH (Growth Hormone Releasing hormone)
VIP (Vasoactive intestinal peptide)