2.4 Synovial Fluid (Microscopic Examination) Flashcards

1
Q

In WBC count for Synovial fluid, dilutions done only on turbid or bloody fluids using?

a. 3% acetic acid
b. Saponin
c. Hypotonic saline
d. Hyaluronidase

A

b and c

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2
Q

Purpose of diluent?

A

Lyse RBC

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3
Q

In differential count for Synovial fluid, requires incubation of the fluid with?

a. 3% acetic acid
b. Saponin
c. Hypotonic saline
d. Hyaluronidase

A

Hyaluronidase

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4
Q

What component of the synovial fluid is responsible for viscosity?

A

Hyaluronic acid

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5
Q

How do you weaken the viscosity of Synovial fluid?

A

Hyaluronidase

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6
Q

Neutrophils is normally seen in synovial fluid in < ___ % of the differential

A

25

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7
Q

CLinical significant

Increase septic or crystal - induced arthritis

a. Neutrophil
b. Lymphocyte
c. Macrophage
d. Synoviocyte

A

a

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8
Q

Lymphocyte is normally seen in Synovial fluid at ___% of the differential

A

15

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9
Q

Macrophage is normally seen in synovial fluid

T or F

A

T

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10
Q

This may be multinucleated resembling a mesothelial cell

a. Neutrophil
b. Lymphocyte
c. Macrophage
d. Synoviocyte

A

d

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11
Q

Clinical significance:

Increase non-septic inflammation

a. Neutrophil
b. Lymphocyte
c. Macrophage
d. Synoviocyte

A

b and c

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12
Q

Synoviocyte is normally seen in regardless if there is clinical significant cases

T or F

A

T

Clinical significance: None

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13
Q

Normal:

Neutrophil with ingested round body

a. LE cells
b. Reiter Cell / Neutrophage
c. Ragocyte
d. Cartilage cell

A

a

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14
Q

Normal:

Neutrophil with dark granules containing immune complexes

a. LE cells
b. Reiter Cell / Neutrophage
c. Ragocyte
d. Cartilage cell

A

c

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15
Q

Normal:

Macrophage with ingested neutrophils

a. LE cells
b. Reiter Cell / Neutrophage
c. Ragocyte
d. Cartilage cell

A

b

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16
Q

Normal:

Large, multinucleated cells

a. LE cells
b. Reiter Cell / Neutrophage
c. Ragocyte
d. Cartilage cell

A

d

17
Q

Clinical significance:

SLE

a. LE cells
b. Reiter Cell / Neutrophage
c. Ragocyte
d. Cartilage cell

A

a

18
Q

Clinical significance

Rheumatoid arthritis

a. LE cells
b. Reiter Cell / Neutrophage
c. Ragocyte
d. Cartilage cell

A

c

19
Q

Clinical significance:

Osteoarthritis

a. LE cells
b. Reiter Cell / Neutrophage
c. Ragocyte
d. Cartilage cell

A

d

20
Q

Clinical significance:

Reiter’s syndrome

a. LE cells
b. Reiter Cell / Neutrophage
c. Ragocyte
d. Cartilage cell

A

b

21
Q

Normal:

Microscopically show collagen and fibrin

a. Rice bodies
b. Fat droplets
c. Hemosiderin

A

a

22
Q

Normal:

Refractile globules, Sudan +

a. Rice bodies
b. Fat droplets
c. Hemosiderin

A

b

23
Q

Normal:

Inclusion within clusters of synovial cells

a. Rice bodies
b. Fat droplets
c. Hemosiderin

A

c

24
Q

Clinical significance:

TB, Septic, and Rheumatoid arthritis

a. Rice bodies
b. Fat droplets
c. Hemosiderin

A

a

25
Q

Clinical significance

Pigmented Villonodular synovitis

a. Rice bodies
b. Fat droplets
c. Hemosiderin

A

c

26
Q

Clinical significance:

Trauma and chronic inflammation

a. Rice bodies
b. Fat droplets
c. Hemosiderin

A

b

27
Q

A stain of choice for hemosiderin?

A

Prussian blue