23. Thromboembolic Drugs Flashcards

1
Q

What is an unfractionated parenteral anticoagulant that indirectly inhibits thrombin and Xa inhibitors?

A

Heparin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

The following are what kind of parenteral anticoagulant which indirectly inhibit thrombin/Xa?
enoxaprin
tinzaprin
dalteaprin

A

Low molecular weight heparins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

The following are what kind of parenteral anticoagulant which indirectly inhibit thrombin/Xa?
fondaparinux

A

synthetic pentsaccharide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

The following are what kind of parenteral anticoagulants which directly inhibit?
Bivalirudin
argatroban

A

thrombin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is a kind of oral anticoagulants which has a coumarin derivative?

A

warfarin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

The following are direct oral anticoagulants (DOAC) which inhibit factor…?
Rivaroxaban
apixaban
endoxaban

A

factor Xa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

The following are direct oral anticoagulants that inhibit?

Dabigatran

A

thrombin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

The follow is an oral antiplatelet that inhibits synthesis of?
Aspirin ASA

A

thromboxane A2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

The follow are oral antiplatelets which block what receptor?
Clopidogrel
Prasugrel
Ticagrelor

A

ADP receptor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

The follow are oral antiplatelets that inhibit?
dipyridamole
cilostazol

A

phosephodiesterase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

The following are parenteral antiplatelet drugs which block platelet…?
abciximab
eptifibatide
tirofiban

A

platelet glycoprotein inhibitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q
The follow are parenteral thrombolytic/ fibrolytic drugs, which is missing?
tPA like: alteplase
reteplase
tenecteplase
and?
A

urokinase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Why does cutaneous necrosis occur in warfarin?

A

protein c has a shorter half like than factor 7 clotting factor, so warfarin administration can initially cause a pro-coagulant state- it is why you give it with heparin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly