23- Parathyroid gland: Calcitriol - Calcitonin - Hormones

Question 1

How does Ca influences the n.s

Answer 1

Hyper-Calcemia = depression of N.S
Hypo-Calcemia = Excites N.S .. due to increansed permeability to Na

Question 2

Where is the highest concentration of phosphate found in?

Answer 2

85% in bone

Question 3

What is tetany?

Answer 3

When Ca levels drop, causing excitation and discharge spontaenous muscle contraction/seizures

Question 4

what are the bone salts?

Answer 4

Ca , P , OH-Patitte

Question 5

How are Hydroxyappetite formed

Answer 5

Ca salt precipitates when collagen monomers polymerize in fibers..formin osteoids.. and these osteoid capture the osteo-blasts .. Forming on surfaces Hydroxyappetite crystals

Question 6

Where is the site of most of the exchangeable ca?

Answer 6

Bone

Question 7

What effect does Vit.D have on the stomach?

Answer 7

It helps absorb Ca

Question 8

How does Ca infulence 1,25di-Ohcholecalciferol

Answer 8

If ca is high = 1,25dioh… formation is lowered

Question 9

what action does 1,25dioh.. have?

Answer 9

Acts on gut, kidney and bones to inc ca/P absorption into the ECF

Question 10

What effects can Vit.D have in smaller quantities

Answer 10

Well it can promote bone calcification..
Increasing Ca/P absorbtion in GIT
And
Enhancing mineralization

Question 11

What can PTH do to the body?

Answer 11

Lowering P [ ] = Dec Tubular re-absortion of P and Na and K

Increase Ca, Mg, H [ ] in tubules

Question 12

What can PTH do?

Answer 12

Destroy bone, but due to big excess of Ca in bone .. there is not a immediate effect its longterm.